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Organic Chemistry II - CHEM 202

Covers carbonyl chemistry, aromatic compounds, amines, spectroscopy, synthesis strategies, and advanced reaction mechanisms.

Study Tools

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Study guides

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04 Aromatic Compounds in Synthesis

Learn how substitution, reduction, and cross-coupling reactions can be combined to control the structure of aromatic compounds.
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05 Aldehydes and Ketones: Nucleophilic Addition

Learn how aldehydes and ketones react with carbon and nitrogen nucleophiles, how these reactions form alcohols, imines, and enamines, and how to choose conditions for synthesis.
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07 Carboxylic Acid Derivatives and Acyl Substitution

Learn how carboxylic acid derivatives differ in reactivity, how nucleophilic acyl substitution proceeds, and how to predict products from common reactions.
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03 Aromaticity and Electrophilic Aromatic Substitution

Understand why aromatic rings favor substitution, how electrophilic aromatic substitution proceeds, and how substituents guide reaction rates and product positions.
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09 Advanced Reaction Mechanisms

Connect rearrangement pathways, orbital symmetry, stereochemical outcomes, and kinetic evidence to evaluate advanced organic reaction mechanisms.
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10 Retrosynthesis and Synthesis Design

Learn how to plan organic syntheses backward from a target, then evaluate the proposed route by checking reactions, selectivity, and step order.
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06 Enols, Enolates, and Carbon–Carbon Bond Formation

Learn how carbonyl compounds form enols and enolates, and how enolates create carbon–carbon bonds in aldol, alkylation, Claisen, and Michael reactions.
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08 Amines and Nitrogen-Containing Functional Groups

Understand how amine structure controls basicity and reactivity, and how amines are prepared and transformed in organic synthesis.
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02 Spectroscopic Structure Elucidation

Learn how to combine mass spectrometry, infrared spectroscopy, and NMR evidence to identify an unknown organic structure.
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01 Mechanistic Foundations and Reactive Intermediates

Learn how to trace electron flow, compare acids and bases, evaluate leaving groups, and reason about intermediates in organic reaction mechanisms.
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Quizzes

10

05 Aldehydes and Ketones: Nucleophilic Addition

A medium-difficulty quiz on nucleophilic addition to aldehydes and ketones, Grignard reactions, and reactions with nitrogen nucleophiles.
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08 Amines and Nitrogen-Containing Functional Groups

A medium-difficulty quiz on amine structure, basicity, synthesis, separation, and reactions.
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03 Aromaticity and Electrophilic Aromatic Substitution

A medium-difficulty quiz on aromaticity, electrophilic aromatic substitution, and substituent effects.
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06 Enols, Enolates, and Carbon–Carbon Bond Formation

A medium-difficulty quiz on enol and enolate formation, selectivity, and carbon–carbon bond-forming reactions.
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09 Advanced Reaction Mechanisms

An application-focused quiz on rearrangements, pericyclic reactions, stereochemistry, and experimental tests of reaction mechanisms.
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04 Aromatic Compounds in Synthesis

A medium-difficulty quiz on reaction selection, mechanisms, and synthesis planning for aromatic compounds.
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10 Retrosynthesis and Synthesis Design

A medium-difficulty quiz on retrosynthetic reasoning, synthesis planning, selectivity, and route evaluation.
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01 Mechanistic Foundations and Reactive Intermediates

A medium-difficulty quiz on electron flow, acid–base behavior, nucleophiles, leaving groups, and reactive intermediates.
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02 Spectroscopic Structure Elucidation

A medium-difficulty quiz on combining mass spectrometry, infrared spectroscopy, and NMR evidence to elucidate organic structures.
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07 Carboxylic Acid Derivatives and Acyl Substitution

A medium-difficulty quiz on the reactivity, mechanisms, and product prediction of carboxylic acid derivatives.
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Flashcards

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06 Enols, Enolates, and Carbon–Carbon Bond Formation

Review how enols and enolates form and how enolate chemistry builds carbon–carbon bonds in aldol, alkylation, Claisen, and Michael reactions.
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02 Spectroscopic Structure Elucidation

Practice how mass spectrometry, infrared spectroscopy, and NMR evidence work together to identify unknown organic structures.
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03 Aromaticity and Electrophilic Aromatic Substitution

Review the principles of aromaticity, the electrophilic aromatic substitution mechanism, and how substituents influence reaction rates and product positions.
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05 Aldehydes and Ketones: Nucleophilic Addition

Review how nucleophiles add to aldehydes and ketones, how organometallic reagents form alcohols, and how amines produce imines or enamines.
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04 Aromatic Compounds in Synthesis

Review how aromatic substitution, reductions, diazonium chemistry, and cross-coupling help build substituted arenes and biaryls.
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10 Retrosynthesis and Synthesis Design

Practice working backward from organic targets, choosing strategic disconnections, and evaluating plausible forward synthesis routes.
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09 Advanced Reaction Mechanisms

Review rearrangements, pericyclic reaction rules, and experimental evidence used to evaluate organic reaction mechanisms.
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07 Carboxylic Acid Derivatives and Acyl Substitution

Review the structures, reactivity, mechanism, and product prediction of carboxylic acid derivatives undergoing nucleophilic acyl substitution.
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08 Amines and Nitrogen-Containing Functional Groups

Review how amines are classified, how their nitrogen lone pair shapes their behavior, and how amines are prepared and transformed.
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01 Mechanistic Foundations and Reactive Intermediates

Review electron-flow conventions, acid–base behavior, nucleophiles, leaving groups, and the stability and role of common organic reaction intermediates.
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