What are three key functions of phosphate?
Phosphate supports cellular energy, muscle and nerve function, and bone structure.
Study 5 Phosphate Imbalances with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
What are three key functions of phosphate?
Phosphate supports cellular energy, muscle and nerve function, and bone structure.
What is a commonly used adult serum phosphate range?
A commonly used adult serum reference range is 2.5–4.5 mg/dL; follow the laboratory’s reference range.
What level defines hypophosphatemia?
Hypophosphatemia is a blood phosphate level below 2.5 mg/dL.
What level defines hyperphosphatemia?
Hyperphosphatemia is a blood phosphate level above 4.5 mg/dL.
Why can refeeding after prolonged undernutrition lower blood phosphate?
Refeeding after prolonged undernutrition can shift phosphate into cells, causing hypophosphatemia.
Which conditions can cause hypophosphatemia through low intake or absorption?
Low intake or absorption can result from starvation, malnutrition, alcohol use disorder, or malabsorption.
What serious problems can severe hypophosphatemia cause?
Severe or prolonged depletion can cause muscle weakness, respiratory muscle failure, rhabdomyolysis, confusion, seizures, or coma.
What should be assessed and monitored in suspected hypophosphatemia?
Assess strength, respiratory effort, mental status, and signs of muscle injury; monitor phosphate, calcium, potassium, magnesium, and renal function.
What is a key safety concern when replacing phosphate?
Give phosphate only as prescribed. Excessive or rapid replacement can cause hypocalcemia and dangerous calcium-phosphate deposits.
What is the most common cause of hyperphosphatemia?
Reduced kidney excretion is the most common cause, especially in advanced chronic kidney disease.
Which conditions can raise phosphate through cell damage?
Rhabdomyolysis, crush injury, tumor lysis syndrome, and diabetic ketoacidosis can release phosphate from damaged cells.
Why can hyperphosphatemia cause tingling or muscle cramps?
Excess phosphate can lower available calcium. Tingling, cramps, twitching, tetany, and seizures may reflect associated hypocalcemia.
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