A drug that activates a receptor is acting as an agonist.
02 How Medicines Work in the Body Online Quiz Questions
Use this free practice quiz with 20 questions to review 02 How Medicines Work in the Body, test your knowledge, and prepare for your next test or exam.
A patient’s delayed stomach emptying changes how quickly an oral medicine takes effect. Which pharmacokinetic process is most directly affected?
- A
Distribution
- B
Absorption
- C
Excretion
- D
Pharmacodynamics
When an oral medicine is metabolized in the gut or liver before reaching circulation, this is called the .
What is the term for the intended benefit produced by a medicine?
A medicine binds to blood proteins. Which portion is generally readily available to act on body tissues?
- A
The portion bound to blood proteins
- B
The portion already excreted
- C
The unbound portion
- D
The portion stored in the digestive tract
What is the technical term for the processes describing how the body handles a drug?
A medicine is inactive when given but becomes active after chemical alteration by the body. Which statement best explains this change?
- A
It always makes a drug inactive.
- B
It can activate a drug that was initially inactive.
- C
It only changes a drug's route of administration.
- D
It prevents a drug from interacting with its targets.
Which can serve as targets that drugs interact with to produce effects? Select all correct choices.
- A
Receptors
- B
Enzymes
- C
Ion channels
- D
Bile
- E
Stool
If a patient has difficulty swallowing a medicine, it is safe to crush or split the dosage form whenever doing so would make it easier to take.
- A
True
- B
False
The removal of a drug or its metabolites from the body is . The time it takes for the drug's amount or concentration to fall by about half is its .
Before administering a medicine, which actions are appropriate safety checks? Select all correct choices.
- A
Verify the patient and medicine.
- B
Check the dose, route, and time.
- C
Review relevant allergies and vital signs.
- D
Review relevant laboratory results and precautions.
- E
Change the route if the ordered route seems inconvenient.
Why can a small change in dose or concentration be important for a medicine with a narrow therapeutic range?
- A
Large changes in concentration are always needed to affect the response.
- B
Small changes in dose or concentration can affect the balance of benefits and risks.
- C
The medicine cannot cause adverse reactions.
- D
The medicine is not affected by patient-specific factors.
One medicine inhibits an enzyme that breaks down another medicine. What effect may this interaction have on the second medicine?
- A
It always speeds up the other drug's excretion.
- B
It prevents the other drug from being absorbed.
- C
It can raise the other drug's concentration.
- D
It guarantees the other drug will have no adverse reactions.
After giving a medicine expected to lower a patient's blood pressure, describe how you would assess the response and what you would do if it were concerning or unexpected.
An agonist activates a receptor, while an antagonist blocks or reduces its activation.
- A
True
- B
False
What term describes a drug’s effects and how it produces them?
Which statement best describes how blood flow can affect a drug’s distribution into body tissues?
- A
Blood flow has no effect on distribution.
- B
Blood flow can affect distribution into body tissues.
- C
Blood flow converts the drug into an active metabolite.
- D
Blood flow determines whether the drug is excreted in stool.
Which route of administration allows a medicine to enter the circulation directly?
A patient starts a medicine that induces an enzyme responsible for breaking down another medicine. What change may result for the other medicine?
- A
It always prevents the other medicine from being absorbed.
- B
It raises the other medicine’s concentration by slowing its breakdown.
- C
It can lower the other medicine’s concentration by increasing its breakdown.
- D
It prevents the other medicine from reaching any body tissues.
A patient’s kidney function has declined. For a drug that is normally removed by the kidneys, what is a possible consequence?
- A
Certain drugs may be removed more slowly and accumulate.
- B
All drugs will be metabolized more rapidly in the liver.
- C
The drug will be prevented from binding to blood proteins.
- D
The drug will immediately stop producing any effect.