A person with type 2 diabetes who takes metformin has an eGFR of 28 mL/min/1.73 m². Which point is most important to discuss with the prescriber?
2 Medications for Diabetes Beyond Insulin Online Quiz Questions
Use this free practice quiz with 20 questions to review 2 Medications for Diabetes Beyond Insulin, test your knowledge, and prepare for your next test or exam.
A person taking glipizide plans to skip breakfast. Which explanation best describes why this could increase the risk of low blood glucose?
- A
Glipizide only works when glucose is excreted in the urine.
- B
Glipizide stimulates insulin release, which can lower glucose even if breakfast is missed.
- C
Glipizide slows carbohydrate absorption in the intestine.
- D
Glipizide replaces insulin that the pancreas cannot make.
A patient asks how an SGLT2 inhibitor such as empagliflozin lowers blood glucose. Which mechanism should you explain?
- A
They slow the breakdown of incretin hormones.
- B
They stimulate pancreatic beta cells to release insulin.
- C
They reduce kidney reabsorption of glucose, increasing glucose excretion in urine.
- D
They slow digestion and absorption of carbohydrates in the intestine.
Select all medicine classes that may be recommended for health benefits for many people with type 2 diabetes and heart failure, chronic kidney disease, or cardiovascular disease, even when additional glucose lowering is not needed.
- A
An SGLT2 inhibitor
- B
A sulfonylurea
- C
A GLP-1–based medicine
- D
An alpha-glucosidase inhibitor
A patient starting an SGLT2 inhibitor asks about possible safety concerns. Select all risks identified for this medicine class.
- A
Genital yeast infections
- B
Ketoacidosis that can occur without markedly elevated blood glucose
- C
Severe hypoglycemia as an inevitable effect when used alone
- D
Volume depletion
True or false: GLP-1–based medicines are used to treat type 1 diabetes.
- A
True
- B
False
True or false: If hypoglycemia occurs while taking acarbose with another glucose-lowering medicine, table sugar is recommended over glucose for raising blood glucose promptly.
- A
True
- B
False
Which medicine class stimulates short-acting insulin release around mealtimes?
Which vitamin deficiency can long-term metformin use contribute to?
Pioglitazone is a thiazolidinedione. This medicine class can cause and .
Take acarbose with the of the meal as directed. If hypoglycemia occurs while taking it with another glucose-lowering medicine, use rather than table sugar.
Explain why selecting a non-insulin diabetes medicine requires considering more than its ability to lower blood glucose. Identify at least three patient-specific factors that can guide the choice.
According to semaglutide prescribing information, which history is a reason not to use the medicine?
- A
A personal or family history of medullary thyroid carcinoma
- B
Seasonal allergies
- C
Controlled hypertension
- D
Prior use of metformin
Below what eGFR value, in mL/min/1.73 m², is metformin contraindicated?
A person newly taking metformin has mild gastrointestinal effects and asks what commonly helps. Which response is best?
- A
Increase the dose gradually and take it with food, as directed.
- B
Add a DPP-4 inhibitor because the combination is required to prevent nausea.
- C
Take each dose on an empty stomach to reduce gastrointestinal effects.
- D
Stop the medicine permanently because gastrointestinal effects cannot improve.
A patient taking a DPP-4 inhibitor is prescribed a GLP-1–based medicine. Which point about using both medicines together is most accurate?
- A
The combination is generally recommended because it greatly increases glucose lowering.
- B
The combination is generally not used because it adds little glucose-lowering benefit.
- C
The combination is necessary to prevent kidney complications.
- D
The combination is required to avoid gastrointestinal effects.
A person who uses mealtime insulin asks whether pramlintide can replace their insulin. Which response is most accurate?
- A
It replaces mealtime insulin because it raises insulin sensitivity.
- B
It is used only to prevent kidney complications and is taken instead of other medicines.
- C
It may be added to mealtime insulin for some people, but it does not replace insulin.
- D
It is an oral medicine that stimulates the pancreas to release insulin at meals.
A patient considering sitagliptin is concerned about weight gain and low blood glucose, and their kidney function is being reviewed. Which summary best addresses these concerns?
- A
DPP-4 inhibitors are usually weight-neutral and have low hypoglycemia risk when used alone, though some need kidney-based dose adjustment.
- B
DPP-4 inhibitors usually cause substantial weight gain and frequent hypoglycemia when used alone.
- C
DPP-4 inhibitors always require the same dose regardless of kidney function.
- D
DPP-4 inhibitors work by slowing carbohydrate absorption in the intestine.
True or false: When a patient starts a GLP-1–based medicine, gradual dose escalation is often used because gastrointestinal effects can occur.
- A
True
- B
False
Which medication class slows the breakdown of incretin hormones, thereby supporting glucose-dependent insulin release and reducing glucagon?
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