Warfarin is an oral vitamin K antagonist used to prevent and treat thromboembolism. True or false?
2 Warfarin Therapy Online Quiz Questions
Use this free practice quiz with 20 questions to review 2 Warfarin Therapy, test your knowledge, and prepare for your next test or exam.
Which enzyme does warfarin inhibit to reduce activation of vitamin K-dependent clotting factors?
Warfarin reduces activation of the vitamin K-dependent clotting factors .
Why does warfarin’s full antithrombotic effect take several days to develop?
- A
Warfarin must accumulate in the bloodstream for several days before it can bind to clotting factors.
- B
Existing circulating clotting factors are not immediately removed.
- C
The body must first produce extra vitamin K.
- D
The INR test cannot detect warfarin’s effect during the first few days.
Which laboratory measure guides warfarin dose adjustment?
- A
Activated partial thromboplastin time (aPTT) alone
- B
Platelet count
- C
Prothrombin time expressed as the INR
- D
Serum vitamin K concentration
Which factors can affect an individual patient’s warfarin dose needs? Select all correct answers.
- A
Age
- B
Body weight
- C
Other medicines
- D
Comorbidities
- E
Genetic variation in CYP2C9 or VKORC1
- F
Eye color
- G
Blood type
If a patient misses a warfarin dose, the patient should double the next day’s dose to make it up. True or false?
- A
True
- B
False
A patient with venous thromboembolism has an INR goal of 2–3. Which statement best explains how this goal relates to warfarin treatment generally?
- A
An INR goal of 2–3 is required for every person taking warfarin.
- B
An INR goal of 2–3 is common for some conditions, but it is not universal.
- C
INR goals apply only to people taking warfarin for atrial fibrillation.
- D
A mechanical heart valve always means that INR monitoring is unnecessary.
For a person taking warfarin, the general dietary goal is a of vitamin K.
Besides congenital malformations, what fetal complication is identified as a possible harm from warfarin during pregnancy?
A patient whose warfarin treatment has been stable starts an antibiotic and sharply increases their intake of leafy greens. What should the patient do, and why?
Which measures are supported as part of the general approach to major, life-threatening warfarin-associated bleeding? Select all correct answers.
- A
Stop warfarin.
- B
Give intravenous vitamin K.
- C
Continue warfarin while waiting for the bleeding to resolve.
- D
Give four-factor prothrombin complex concentrate (4F-PCC).
- E
Use plasma if 4F-PCC is unavailable.
- F
Use oral vitamin K alone as a substitute for urgent clinical management.
A patient taking warfarin has an INR of 6 and no clinically relevant bleeding. Which approach best matches the guidance described for this situation?
- A
Immediately give vitamin K to every such patient.
- B
Temporarily withhold warfarin rather than routinely adding vitamin K, with clinician assessment and follow-up.
- C
Continue the usual warfarin dose and do not recheck the INR.
- D
Give plasma as routine treatment despite the absence of bleeding.
For a pregnant patient with a mechanical heart valve, stopping warfarin can also pose serious risks. True or false?
- A
True
- B
False
Which laboratory test is used to guide warfarin dose adjustment?
- A
Activated partial thromboplastin time
- B
Prothrombin time expressed as the INR
- C
Platelet count
- D
Serum creatinine
Name one gene whose genetic variation can affect warfarin dose needs. Enter the gene symbol.
A patient taking warfarin misses a dose. Which instruction is supported by the guidance in the material?
- A
Double the next dose
- B
Take extra doses over the next two days
- C
Do not double the next day's dose to make up for it
- D
Stop warfarin permanently
A patient on stable warfarin starts an antibiotic and sharply increases their intake of leafy greens. What should they do?
- A
Promptly contact the anticoagulation clinician for advice about monitoring and possible dose changes
- B
Stop warfarin and avoid all leafy greens
- C
Double the warfarin dose to offset the greens
- D
Wait until the next routine appointment without mentioning the changes
Which statement about warfarin dosing in older adults is supported by the material?
- A
Older adults are generally less sensitive and often need higher doses
- B
Older adults may be more sensitive and often need lower doses
- C
Age has no possible effect on dose needs
- D
Older adults should stop INR monitoring
Warfarin reduces activation of several vitamin K-dependent clotting factors. Which two anticoagulant proteins does it also reduce?
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