True or false: A medication interaction can only increase a medicine’s effect; it cannot decrease the effect or cause other harm.
Medication Interactions and Safety: Practice Questions Online Quiz Questions
Use this free practice quiz with 20 questions to review Medication Interactions and Safety:, test your knowledge, and prepare for your next test or exam.
True or false: Because naproxen is available over the counter, a person taking warfarin can assume it is interaction-free.
- A
True
- B
False
What drug class does naproxen belong to?
Vitamin K in kale and spinach can reduce the effect of .
A person taking warfarin plans to add large daily servings of kale and spinach. Which approach is generally recommended?
- A
Avoid kale and spinach completely, regardless of usual diet.
- B
Keep vitamin K intake consistent and discuss major dietary changes with the care team.
- C
Suddenly increase leafy greens so warfarin works more strongly.
- D
Stop warfarin whenever eating leafy greens.
Grapefruit can increase the amount of simvastatin entering the blood. Higher drug levels may increase side effects, including .
A person taking simvastatin regularly drinks grapefruit juice. What is the best next step?
- A
Assume grapefruit is safe because the person takes a statin.
- B
Stop the statin immediately without seeking advice.
- C
Check the specific medicine’s label and ask a pharmacist or prescriber whether to avoid grapefruit or consider another option.
- D
Avoid every fruit while taking any cholesterol medicine.
When checking a person’s medication combinations, which items should be included? Select all that apply.
- A
Prescription medicines
- B
Over-the-counter products
- C
Supplements
- D
Foods
- E
Drinks
- F
Only medicines prescribed by one clinician
A person takes oxycodone and alprazolam together. Which serious outcomes can result from their additive effects? Select all that apply.
- A
Extreme sedation
- B
Dangerously slow or difficult breathing
- C
Coma
- D
Death
- E
Improved alertness
A person uses nitroglycerin for chest pain and asks whether they can take sildenafil. Which response is safest?
- A
They can be combined if taken with food.
- B
They must not be combined because the combination can cause a dangerous drop in blood pressure.
- C
They can be combined as long as the person takes less nitroglycerin.
- D
They interact only if the person also eats leafy greens.
True or false: After taking an opioid and a benzodiazepine together, trouble breathing or being unable to stay awake requires emergency help.
- A
True
- B
False
A dangerous drop in what body measure can occur when sildenafil is combined with nitroglycerin?
A person with prescriptions for oxycodone and alprazolam asks whether they can take both together without checking with a clinician. Explain the main interaction risk and the appropriate safety response.
A person has prescriptions for oxycodone and alprazolam. Which plan best reflects the safety guidance for this combination?
- A
Take both as prescribed without telling the prescriber.
- B
Add alcohol to reduce the chance of pain or anxiety.
- C
Do not combine them on their own; seek prescriber oversight and do not add alcohol or other sedating medicines.
- D
Take an extra dose of either medicine if sedation does not occur.
A person taking warfarin is considering naproxen for pain. What is the safest advice?
- A
Check with a pharmacist or prescriber before taking naproxen because the combination can increase bleeding risk.
- B
Assume naproxen is safe because it is sold over the counter.
- C
Stop warfarin and take naproxen instead without seeking advice.
- D
Take naproxen only with grapefruit juice.
A person taking simvastatin regularly drinks grapefruit juice. Which response best addresses the potential interaction?
- A
Grapefruit reduces the amount of simvastatin in the blood, so the person should increase the dose.
- B
Grapefruit can increase simvastatin levels and side-effect risk, so the person should check the specific medicine with a pharmacist or prescriber.
- C
Grapefruit interacts with every statin in exactly the same way, so the person should stop all statins.
- D
Grapefruit has no effect on medicine levels, so no follow-up is needed.
Which nutrient in kale and spinach can reduce warfarin’s effect?
A person taking warfarin is considering naproxen for pain. What potential harm should they recognize, and what is the safest next step?
- A
Naproxen reliably prevents warfarin-related bleeding, so it can be taken without checking.
- B
The only concern is that naproxen may make leafy greens less nutritious.
- C
The combination can increase the risk of serious bleeding, so the person should check with a pharmacist or prescriber before taking naproxen.
- D
Over-the-counter medicines cannot interact with prescription medicines.
What interaction term describes two medicines whose effects combine, potentially intensifying effects such as sedation?
A person has prescriptions for oxycodone and alprazolam. Why should they not combine the medicines on their own?
- A
The medicines cancel each other out, so the person can take them together without oversight.
- B
Their effects can add together, causing extreme sedation and dangerously slow or difficult breathing; the person should not combine them without prescriber oversight.
- C
The combination only changes the taste of food and has no serious safety risk.
- D
The combination is safe as long as the medicines were prescribed separately.