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Free Practice Quiz Question List

09 Molecular Genetics and Gene Expression Online Quiz Questions

Use this free practice quiz with 20 questions to review 09 Molecular Genetics and Gene Expression, test your knowledge, and prepare for your next test or exam.

20 questions
01
Choose one
1 point

Which statement correctly distinguishes transcription from translation?

  1. A

    Translation uses a DNA template to make RNA.

  2. B

    Transcription uses a DNA template to make RNA.

  3. C

    Replication uses mRNA to make a polypeptide.

  4. D

    Translation copies DNA before cell division.

02
True or false
1 point

In semiconservative DNA replication, each daughter DNA molecule contains one original strand and one newly synthesized strand.

  1. A

    True

  2. B

    False

03
Fill in the blank
1 point

During DNA replication, the enzyme that seals breaks between adjacent Okazaki fragments is .

04
Written response
1 point

An mRNA sequence is 5′–AUG GCU UUU UGA–3′. How many amino acids are added to the polypeptide before translation terminates?

05
Choose one
1 point

Why is the lagging strand synthesized as short Okazaki fragments?

  1. A

    The lagging strand is made continuously because DNA polymerase moves in both directions.

  2. B

    The lagging strand contains RNA instead of DNA.

  3. C

    The lagging strand is made discontinuously because DNA polymerase synthesizes only 5′ to 3′.

  4. D

    The lagging strand is copied without a primer.

06
True or false
1 point

Epigenetic regulation changes the DNA base sequence whenever it alters gene expression.

  1. A

    True

  2. B

    False

07
Fill in the blank
1 point

In eukaryotic RNA processing, the removes introns and joins exons.

08
Choose all
1 point

Which components are required for a standard polymerase chain reaction (PCR)? Select all correct choices.

  1. A

    Template DNA containing the target region

  2. B

    Two primers that flank the target region

  3. C

    Free DNA nucleotides

  4. D

    A heat-stable DNA polymerase such as Taq polymerase

  5. E

    A ribosome to translate the amplified DNA

09
Written response
1 point

Under ideal PCR amplification, one starting DNA molecule doubles in each cycle. How many target molecules are present after three cycles?

10
Choose all
1 point

At which levels can eukaryotic gene expression be regulated? Select all correct choices.

  1. A

    Chromatin accessibility

  2. B

    RNA processing

  3. C

    Translation

  4. D

    Post-translational modification or degradation

  5. E

    The fixed identity of a DNA nucleotide that never changes

11
Choose one
1 point

A coding sequence changes one mRNA codon from UUU to UUC, and both codons specify phenylalanine. How should this mutation be classified?

  1. A

    Frameshift mutation

  2. B

    Silent substitution

  3. C

    Nonsense substitution

  4. D

    Insertion mutation

12
Open ended
1 point

Design an investigation to test whether a specific DNA mutation changes the function of the protein encoded by the gene. Describe the question, variables, controls, measurements, and how the evidence would support or fail to support a conclusion.

13
Choose one
1 point

A researcher wants to identify the exact base substitution in a gene. Which biotechnology method most directly provides that information?

  1. A

    Separating DNA fragments only by their movement through a gel

  2. B

    Determining the order of bases in a DNA molecule

  3. C

    Joining a gene to a vector with DNA ligase

  4. D

    Producing many copies of a target region without reading its sequence

14
Choose one
1 point

A DNA template strand has the sequence 3′–TAC GGA CTT–5′. Which mRNA sequence would RNA polymerase produce?

  1. A

    5′–TAC GGA CTT–3′

  2. B

    5′–AUG CCU GAA–3′

  3. C

    3′–AUG CCU GAA–5′

  4. D

    5′–UAC GGA CUU–3′

15
Choose one
1 point

Why does DNA replication produce Okazaki fragments on the lagging strand?

  1. A

    The leading strand, because it is synthesized 3′ to 5′

  2. B

    The leading strand, because it is synthesized in Okazaki fragments

  3. C

    The lagging strand, because it is synthesized discontinuously

  4. D

    The lagging strand, because DNA polymerase synthesizes it 3′ to 5′

16
Choose one
1 point

A ribosome translates the mRNA sequence 5′–AUG GCU UUU UGA–3′. What polypeptide sequence is produced?

  1. A

    Methionine–alanine–phenylalanine

  2. B

    Alanine–phenylalanine–methionine

  3. C

    Methionine–phenylalanine–alanine

  4. D

    Methionine–alanine–phenylalanine–tryptophan

17
Choose one
1 point

A single nucleotide is inserted near the beginning of a protein-coding sequence. Which outcome is most likely if the insertion is not repaired?

  1. A

    Silent mutation

  2. B

    Missense mutation

  3. C

    Nonsense mutation

  4. D

    Frameshift mutation

18
True or false
1 point

True or false: Epigenetic regulation can alter gene activity without changing the DNA base sequence.

  1. A

    True

  2. B

    False

19
Written response
1 point

A DNA template strand is 3′–TAC GGA CTT–5′. Enter the resulting mRNA sequence from 5′ to 3′, with spaces between codons.

20
Written response
1 point

After one round of semiconservative DNA replication, how many parental DNA strands are present in each daughter DNA molecule? Enter a whole number.