Neural adaptation is related to plasticity, but is not identical to learning.
6 Learning and Neural Plasticity Online Quiz Questions
Use this free practice quiz with 20 questions to review 6 Learning and Neural Plasticity, test your knowledge, and prepare for your next test or exam.
A neuron's response diminishes while it is exposed to an unchanging stimulus. What process does this illustrate? Enter the name of the process.
At many excitatory synapses, which sequence best explains how coincident presynaptic activity and postsynaptic depolarization can produce long-term potentiation?
- A
Depolarization closes NMDA receptors, reducing calcium entry and removing AMPA receptors.
- B
Depolarization relieves the NMDA receptor block, allowing calcium entry that can increase AMPA receptor number or effectiveness.
- C
Postsynaptic depolarization prevents presynaptic activity from influencing the synapse.
- D
Calcium entry directly weakens the synapse by reducing AMPA receptor effectiveness.
A lasting increase in synaptic strength is called , while a lasting decrease in synaptic strength is called .
At some hippocampal synapses, how can a more modest rise in postsynaptic calcium contribute to long-term depression (LTD)?
- A
A large calcium rise invariably increases AMPA receptors, regardless of synapse type.
- B
A modest calcium rise strengthens transmission by increasing the number of AMPA receptors.
- C
A modest calcium rise can favor signaling that removes or reduces AMPA receptors, weakening transmission.
- D
LTD occurs only when presynaptic firing stops.
Which statements about spike-timing-dependent plasticity are supported? Select all correct answers.
- A
Presynaptic firing shortly before postsynaptic firing can favor strengthening.
- B
The timing rule is identical in every circuit and condition.
- C
The reverse firing order can favor weakening.
- D
Relative firing time cannot influence synaptic change.
A neuromodulator that can signal whether an outcome was rewarding, unexpected, or otherwise important is .
Some forms of long-term potentiation involve changes on the presynaptic side as well as postsynaptic changes.
- A
True
- B
False
Which statements describe processes associated with early and longer-lasting plasticity? Select all correct answers.
- A
Early plasticity may rely on modifying existing proteins and receptors.
- B
Early plasticity always requires structural changes to synapses.
- C
Longer-lasting change involves only temporary changes to existing receptors.
- D
Longer-lasting change can involve altered gene expression, protein production, and structural changes to synapses.
A neuron's prior activity changes how easily it undergoes further plasticity. What is this regulation of future plastic change called? Enter the term.
Which process can stabilize overall activity by adjusting many of a neuron's excitatory synapses up or down in response to prolonged changes in activity?
- A
Hebbian plasticity modifies particular active connections.
- B
Synaptic scaling adjusts many excitatory synapses up or down in response to prolonged changes in activity.
- C
Neural adaptation prevents any activity-dependent changes at synapses.
- D
Spike-timing-dependent plasticity stabilizes activity by changing all excitatory synapses equally.
Explain how synapse-specific plasticity and stabilizing mechanisms can allow neural circuits to adapt without becoming unstable. Include the role of homeostatic plasticity and metaplasticity.
Although many described LTP mechanisms involve postsynaptic changes, some forms also involve changes on which side of the synapse? Enter the side of the synapse.
A circuit repeatedly uses one input while leaving nearby inputs relatively inactive. Which outcome is consistent with activity-dependent synaptic plasticity?
- A
Every synapse must strengthen whenever a neuron fires.
- B
The changes can be specific to synapses that were active.
- C
Plasticity only changes how sensory receptors detect stimuli.
- D
Synaptic changes occur independently of activity.
At a hippocampal synapse, a modest rise in postsynaptic calcium is followed by weaker transmission. Which mechanism best fits this outcome?
- A
A large calcium rise always adds AMPA receptors, regardless of context.
- B
Presynaptic firing stops permanently, eliminating all transmission.
- C
A modest postsynaptic calcium rise can favor reducing AMPA receptors.
- D
All postsynaptic receptors are converted into NMDA receptors.
In a circuit showing a commonly observed spike-timing-dependent plasticity pattern, what is expected when a presynaptic neuron fires shortly before its postsynaptic target?
- A
Presynaptic firing shortly before postsynaptic firing favors strengthening.
- B
Postsynaptic firing must always precede presynaptic firing for strengthening.
- C
The relative timing of firing has no influence on synaptic change.
- D
Presynaptic and postsynaptic firing must be separated by a long interval.
A synaptic change persists beyond the early phase, when existing proteins and receptors may be modified. Which set of processes can help stabilize longer-lasting change?
- A
Only a brief change in membrane voltage is needed.
- B
Neural adaptation prevents new proteins from being produced.
- C
Long-term changes require every neuron in the brain to fire together.
- D
Altered gene expression, protein production, and synaptic structure can help stabilize change.
A neuron responds less strongly after prolonged exposure to an unchanging stimulus. Which process best describes this change in responsiveness?
- A
Long-term potentiation: synaptic strength increases after activity.
- B
Neural adaptation: responsiveness changes following sustained or repeated stimulation, and a response to an unchanging stimulus may diminish.
- C
Homeostatic plasticity: a particular active connection strengthens without constraint.
- D
Long-term depression: a neuron stops responding to all sensory input.
True or false: A single synaptic change, by itself, fully explains how a complex memory is represented.
- A
True
- B
False
At many excitatory synapses, which receptor type allows calcium ions to enter the postsynaptic neuron after depolarization relieves its voltage-dependent block?