3 Cirrhosis Free Online FlashCards

What is cirrhosis?

Cirrhosis is advanced, diffuse liver scarring that disrupts normal liver structure and function.

What are three common broad causes of cirrhosis?

The three common broad causes are alcohol-associated liver disease, metabolic dysfunction–associated steatotic liver disease, and chronic hepatitis B or C.

Can a person have more than one cause of cirrhosis?

Yes. More than one cause may contribute to cirrhosis in the same person.

Name several less-common causes of cirrhosis.

Other causes include autoimmune hepatitis, bile duct diseases, inherited conditions such as hemochromatosis or Wilson disease, and some medications.

How may early cirrhosis present?

Early cirrhosis may cause few or no symptoms.

What are possible manifestations of cirrhosis?

Possible manifestations include fatigue, poor appetite, muscle loss, itching, jaundice, easy bruising or bleeding, and leg edema.

Which serious complications can arise with cirrhosis?

Portal hypertension and reduced liver function can lead to ascites, variceal bleeding, and hepatic encephalopathy.

How is compensated cirrhosis distinguished from decompensated cirrhosis?

Cirrhosis is described as compensated when no overt decompensating event has occurred; ascites, encephalopathy, or portal-hypertensive gastrointestinal bleeding indicate decompensation.

What does clinical assessment for cirrhosis combine?

Assessment combines the history, physical examination, laboratory tests, and imaging.

Which risk factors or history details may be explored when assessing cirrhosis?

The history may explore alcohol use, metabolic conditions, viral hepatitis, medications and supplements, and family history.

What can blood tests and imaging contribute to cirrhosis assessment?

Blood tests can assess liver injury and function, blood counts, clotting, and possible causes. Ultrasound and elastography can help assess liver structure and stiffness.

When may a liver biopsy be used in cirrhosis assessment?

Biopsy may be used when noninvasive assessment does not resolve the diagnosis or cause.