1 Liver Function and Injury Patterns Online Quiz Questions

In a liver lobule, blood flows from the portal-triad region toward the central vein, while bile flows toward bile ducts in the opposite direction.

A patient has an elevated AST. Which statement is most accurate?

A patient has elevated ALP but normal ALT and AST. Which additional test can help determine whether the ALP elevation is hepatobiliary in origin?

Which activities are performed by hepatocytes? Select all that apply.

Using the same sample, ALT is $360\,\mathrm{U/L}$ with an upper limit of normal of $40\,\mathrm{U/L}$, and ALP is $180\,\mathrm{U/L}$ with an upper limit of normal of $120\,\mathrm{U/L}$. Calculate the R value using $R = \frac{\frac{ALT}{ALT\ ULN}}{\frac{ALP}{ALP\ ULN}}$.

Which liver-lobule region is relatively vulnerable to reduced oxygen delivery?

Which conditions or circumstances can cause low albumin apart from chronic liver dysfunction? Select all that apply.

Which statement about unconjugated bilirubin is accurate?

Which aminotransferase is more liver-specific: ALT or AST?

True or false: In cirrhosis, INR alone is a reliable measure of bleeding risk.

A patient is being evaluated soon after an acute change in liver status. Compare how quickly albumin and PT/INR may respond to changes in liver protein production, and name one factor other than impaired liver production that can affect PT/INR.

In a liver lobule, blood from the portal vein and hepatic artery passes through sinusoids toward which structure?

Which form of bilirubin is water-soluble and may be excreted in urine?

A patient has an elevated AST. Which interpretation is most accurate?

A patient has ALP elevated much more than ALT and AST. What is the most appropriate interpretation of this pattern?

True or false: ALT and AST directly measure how well the liver is functioning.

When ALP is elevated, which additional test can help support a liver or biliary source rather than a source such as bone?

For one sample, $ALT = 240$ U/L with an ALT ULN of $40$ U/L, and $ALP = 240$ U/L with an ALP ULN of $120$ U/L. Calculate the R value using $R = \frac{ALT/ALT\ ULN}{ALP/ALP\ ULN}$. Enter the numerical value.