What is portal hypertension?
Portal hypertension is abnormally increased pressure in the portal venous system.
Study 4 Portal Hypertension with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
What is portal hypertension?
Portal hypertension is abnormally increased pressure in the portal venous system.
What HVPG defines clinically significant portal hypertension in cirrhosis?
In cirrhosis, clinically significant portal hypertension is defined by an HVPG of at least 10 mm Hg.
What are varices, and where are they commonly found?
Varices are enlarged collateral veins, commonly located in the lower esophagus or stomach.
What can cause sudden, severe bleeding in a patient with cirrhosis?
Ruptured esophageal varices can cause sudden, severe gastrointestinal bleeding and require immediate care.
How can portal hypertension cause splenomegaly?
Increased pressure in the splenic venous circulation can cause splenomegaly, or enlargement of the spleen.
Why may portal hypertension with splenomegaly be associated with low platelets?
Hypersplenism can sequester blood cells and contribute to a low platelet count; other blood cell counts may also fall.
What medication approach can reduce first variceal-bleed risk in eligible patients?
For cirrhosis with high-risk varices and no contraindication, nonselective beta-blocker therapy is a preventive option.
What is portal hypertensive gastropathy?
Portal hypertensive gastropathy is congestion of the stomach lining associated with portal hypertension.
What happens to blood flow through portosystemic collaterals?
Portosystemic collaterals can divert intestinal blood around the liver into the systemic circulation.
How can portosystemic shunting contribute to hepatic encephalopathy?
When intestinal blood bypasses the liver, substances normally processed there can reach the systemic circulation and contribute to encephalopathy.
Which fluid-accumulation complication can portal hypertension contribute to?
Portal hypertension can contribute to ascites, the accumulation of fluid in the peritoneal cavity.
How does cirrhosis raise portal pressure?
Cirrhotic scarring increases resistance to blood flow through the liver, raising portal pressure.
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