A patient with liver disease has conjugated hyperbilirubinemia and dark urine. Conjugated bilirubin can enter the urine.
7 Complications of Liver Dysfunction Online Quiz Questions
Use this free practice quiz with 20 questions to review 7 Complications of Liver Dysfunction, test your knowledge, and prepare for your next test or exam.
Which statement best describes thrombosis risk in cirrhosis?
- A
Cirrhosis generally protects against thrombosis.
- B
Cirrhosis can be associated with both bleeding and thrombosis.
- C
Cirrhosis causes bleeding but makes thrombosis impossible.
- D
Thrombosis occurs only when the INR is normal.
A cholestatic laboratory pattern has a disproportionately elevated compared with .
What minimum serum creatinine increase, in mg/dL within 48 hours, meets one acute kidney injury criterion in a patient with cirrhosis?
A patient with cirrhosis develops rapidly worsening jaundice, fever, and right-upper-quadrant pain. What is the best next clinical priority?
- A
Wait several months and repeat the bilirubin level.
- B
Urgently assess for infection and biliary obstruction with laboratory evaluation and appropriate imaging.
- C
Diagnose hemolysis from the jaundice alone.
- D
Treat the bilirubin value without investigating its cause.
A patient with cirrhosis and ascites develops rising creatinine after poor intake and diuretic use. Select all appropriate parts of the initial evaluation.
- A
Assess the patient's volume status.
- B
Assume HRS is the cause before evaluating other possibilities.
- C
Review medications, including diuretics and potentially nephrotoxic drugs.
- D
Look for infection or other precipitating factors.
True or false: In a patient with cirrhosis, INR alone reliably predicts bleeding risk before a low-risk procedure such as diagnostic paracentesis.
- A
True
- B
False
Treatment for HRS-AKI generally combines vasoconstrictor therapy with .
Which vasoconstrictor is named as a recommended option for suitable patients with HRS-AKI? Enter the drug name.
A patient with cirrhosis and ascites has an INR of 2.0 and a platelet count of 78,000/µL, with no active bleeding, and needs diagnostic paracentesis. Which approach is most accurate?
- A
Give plasma to normalize the INR because it reliably predicts bleeding.
- B
Do not routinely correct the INR or platelet count solely for this low-risk procedure; consider the clinical context.
- C
Give vitamin K because it reliably normalizes the INR in cirrhosis.
- D
Avoid the procedure because cirrhosis prevents safe paracentesis.
A hospitalized patient has been diagnosed with HRS-AKI after evaluation of acute kidney injury and precipitating factors. Select all elements of the generally used treatment approach.
- A
Use vasoconstrictor therapy with albumin.
- B
Use NSAIDs to improve renal blood flow.
- C
Monitor for complications such as ischemia or pulmonary edema.
- D
Assess the patient for liver-transplant candidacy.
A patient with cirrhosis and ascites has a creatinine increase of 0.4 mg/dL within 48 hours. There is no shock or clear urinary obstruction, and kidney function does not improve after appropriate volume resuscitation. Which diagnosis should be considered?
- A
Consider HRS-AKI, while continuing to assess for alternative causes.
- B
Diagnose chronic kidney disease from the creatinine rise alone.
- C
Diagnose portal vein thrombosis from the creatinine rise alone.
- D
Exclude HRS-AKI because the patient has ascites.
A patient with cirrhosis and ascites develops a rising serum creatinine. Explain why this finding alone does not establish HRS, and outline the initial evaluation needed before attributing the kidney dysfunction to HRS.
In a patient with conjugated hyperbilirubinemia, dark urine can result because conjugated bilirubin is water-soluble, whereas unconjugated bilirubin is not excreted in urine.
- A
True
- B
False
A patient with chronic liver disease has yellow eyes, dark urine, pale stools, predominantly conjugated hyperbilirubinemia, and alkaline phosphatase elevated out of proportion to aminotransferases. Which process should be considered?
- A
Increased bilirubin production from hemolysis alone
- B
Cholestasis or impaired bile flow, including possible biliary obstruction
- C
Unconjugated bilirubin being excreted in urine
- D
A finding that rules out significant hepatobiliary disease
A patient with cirrhosis and ascites has an INR of 2.0, a platelet count of 78,000/µL, and no active bleeding. They are scheduled for diagnostic paracentesis. Which approach is most accurate?
- A
Give plasma to normalize the INR because it reliably predicts bleeding.
- B
Do not routinely correct the INR before low-risk paracentesis; assess the full clinical context.
- C
Assume thrombosis is unlikely because cirrhosis protects against it.
- D
Give vitamin K because it reliably normalizes INR in cirrhosis.
For acute kidney injury assessment in cirrhosis, what minimum increase in serum creatinine within 48 hours meets the absolute increase criterion? Enter the value in mg/dL.
A patient with cirrhosis and ascites develops rising creatinine after several days of poor oral intake and diuretic use. What is the most appropriate initial approach?
- A
Diagnose HRS immediately and start treatment without further assessment.
- B
Assess volume status, review medications, look for infection or other triggers, and evaluate alternative causes.
- C
Continue diuretics and add an NSAID.
- D
Rule out HRS because the patient has ascites.
A patient with cirrhosis and ascites has a creatinine increase of 0.4 mg/dL within 48 hours. There is no shock or clear urinary obstruction, and kidney function does not improve after appropriate volume resuscitation. Which conclusion is most appropriate?
- A
The creatinine increase alone establishes HRS-AKI.
- B
HRS-AKI should be considered, while assessing for alternative causes and whether kidney function improves after appropriate volume resuscitation.
- C
The increase establishes chronic kidney disease.
- D
The increase establishes portal vein thrombosis.
What is the definitive treatment for hepatorenal syndrome–acute kidney injury in cirrhosis? Enter the treatment in a short term.
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