5 Adjuvant Medications for Pain Free Online FlashCards

What are adjuvant analgesics?

Adjuvant analgesics are medicines developed mainly for purposes other than pain relief that can also reduce particular kinds of pain.

Which antidepressant classes may help neuropathic pain?

SNRIs such as duloxetine and tricyclic antidepressants such as amitriptyline may help neuropathic pain, even when the person is not being treated for depression.

What are possible adverse effects of SNRIs used for pain?

SNRIs can cause nausea or dizziness.

Why can TCAs require extra caution in older adults?

TCAs can cause dry mouth, sleepiness, and dizziness; these effects may increase fall risk, especially in older adults.

Which antiseizure medicines are commonly used for nerve pain?

Gabapentin and pregabalin are commonly used for nerve pain, including pain associated with diabetes or shingles.

How can kidney function affect gabapentin or pregabalin dosing?

Gabapentin and pregabalin doses may need adjustment for kidney function.

What is a key risk of combining gabapentin or pregabalin with opioids?

Combining them with opioids or other central nervous system depressants can increase sedation and the risk of serious breathing problems.

When can topical analgesics be useful?

Lidocaine patches or capsaicin cream or patches may help localized peripheral nerve pain. Applying medicine to a limited area can reduce whole-body exposure compared with oral medicine.

What precautions apply to topical analgesics?

Topical analgesics can cause skin irritation or temporary burning. Use them as directed and avoid contact with eyes and broken skin.

When might corticosteroids be considered for pain?

Dexamethasone and other corticosteroids may be used in selected cases when swelling or inflammation contributes to pain, including some cancer-related pain.

Why should prolonged corticosteroid treatment be monitored?

Corticosteroid risks depend on dose and duration. Prolonged use can cause serious effects and should be monitored by a clinician.

When might a clinician consider bone-targeted treatment for pain?

For cancer that has spread to bone, a clinician may consider bone-targeted treatment as part of the pain plan.