01
True or false
1 point
True or false: Pharmacodynamics describes what the body does to a drug.
Free Practice Quiz Question List
1 Foundations of Pharmacology and Therapeutic Effects Online Quiz Questions
Use this free practice quiz with 20 questions to review 1 Foundations of Pharmacology and Therapeutic Effects, test your knowledge, and prepare for your next test or exam.
20 questions
02
Written response
1 point
What term names the fraction of an administered dose that reaches systemic circulation unchanged?
03
Fill in the blank
1 point
The movement of a drug from blood into tissues and fluids is called .
04
Choose one
1 point
A drug is partly bound to plasma proteins. Which portion is generally more readily available to enter tissues and interact with targets?
- A
Drug bound to plasma proteins
- B
Unbound drug
- C
Drug already excreted in urine
- D
Drug stored in the administration device
05
True or false
1 point
True or false: Genetic information alone predicts how every person will respond to a medication.
- A
True
- B
False
06
Written response
1 point
What term describes a medicine that is converted by metabolism into an active form?
07
Choose all
1 point
A patient's response to a regular medication differs from another person's response to the same dose. Which listed factors can contribute? Select all that apply.
- A
The person's age
- B
Impaired kidney or liver function
- C
The number of letters in the medicine's name
- D
Taking another medicine that alters drug metabolism
08
Fill in the blank
1 point
The range between drug concentrations likely to be effective and those likely to be toxic is the .
09
Choose one
1 point
A medication has a narrow therapeutic window. What does this imply for its use?
- A
The drug cannot produce a therapeutic effect
- B
The drug is necessarily more potent than other drugs
- C
Careful dosing and, for some drugs, monitoring are especially important
- D
The drug is always safe at any dose
10
Choose all
1 point
Which routes can remove drugs or their metabolites from the body? Select all that apply.
- A
Kidneys
- B
Skin as the stated major route
- C
Bile and feces
- D
Lungs for some substances
11
Choose one
1 point
A second medicine inhibits an enzyme that metabolizes a drug taken regularly. What may happen to the first drug's concentration?
- A
Its concentration must fall because metabolism has stopped
- B
Its concentration may rise because it is metabolized more slowly
- C
Its concentration cannot change unless the dose changes
- D
It will always become inactive immediately
12
True or false
1 point
True or false: An adverse drug reaction is a harmful or unwanted response to a medicine at usual doses.
- A
True
- B
False
13
Open ended
1 point
Explain the difference between potency and efficacy. Why does a more potent drug not necessarily produce a greater maximum effect or be safer?
14
Choose one
1 point
A patient takes an oral medicine that undergoes substantial first-pass metabolism. Which outcome best explains why less unchanged drug may reach general circulation?
- A
The drug is distributed into tissues before it enters the blood.
- B
The drug may be metabolized in the intestine or liver before reaching general circulation.
- C
The drug is excreted by the kidneys before it is absorbed.
- D
The drug activates a receptor before entering the systemic circulation.
15
Choose one
1 point
A medicine binds to plasma proteins after entering the blood. Which statement best describes how this binding can affect the medicine's distribution?
- A
The unbound drug is generally more readily available to enter tissues and interact with targets.
- B
The protein-bound drug is always the only portion that can enter tissues.
- C
Protein binding guarantees that the drug will be metabolized into an active form.
- D
Protein binding prevents the drug from reaching the bloodstream.
16
Choose one
1 point
One medicine activates a receptor, while another binds to that receptor and reduces activation by a different substance. How are these medicines best classified, respectively?
- A
Both medicines activate the receptor, but the antagonist produces a longer effect.
- B
The agonist blocks receptor activation, while the antagonist activates it.
- C
The agonist activates the receptor, while the antagonist blocks or reduces activation.
- D
Neither medicine interacts with a biological target.
17
Choose one
1 point
Drug A produces a specified effect at a smaller dose than Drug B. This information alone does not compare their maximum effects. Which conclusion is justified?
- A
Drug A is more efficacious because it produces an effect at a smaller dose.
- B
Drug A is more potent, but the information does not establish which drug has greater efficacy.
- C
Drug B is more potent because it can produce a larger maximum effect.
- D
Drug B is both more potent and more efficacious because it requires a larger dose.
18
Choose one
1 point
A patient has declining kidney function and takes a medicine normally cleared mainly in urine. What change is most likely if the treatment plan is not adjusted?
- A
The drug may remain in the body longer and accumulate with repeated doses.
- B
The drug will necessarily become less potent because the kidneys remove less of it.
- C
The drug will be converted into an active form by the kidneys.
- D
The drug will bypass the bloodstream and enter tissues directly.
19
Written response
1 point
A medicine binds to a protein that catalyzes a biochemical reaction and changes that reaction’s rate. What type of biological target is the protein?
20
Written response
1 point
A medicine changes ion movement across a cell membrane by acting on a membrane protein that forms a passageway for ions. What type of biological target is it acting on?