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2 Metabolic and Respiratory Acid–Base Disorders Online Quiz Questions

Use this free practice quiz with 20 questions to review 2 Metabolic and Respiratory Acid–Base Disorders, test your knowledge, and prepare for your next test or exam.

20 questions
01
True or false
1 point

True or false: In a primary metabolic acid–base disorder, pH and HCO₃⁻ move in the same direction.

  1. A

    True

  2. B

    False

02
Choose one
1 point

An ABG shows pH 7.29, PaCO₂ 32 mm Hg, and HCO₃⁻ 18 mEq/L. Which primary acid–base disorder best explains the pH?

  1. A

    Respiratory acidosis

  2. B

    Metabolic acidosis

  3. C

    Respiratory alkalosis

  4. D

    Metabolic alkalosis

03
Fill in the blank
1 point

In metabolic alkalosis, typical respiratory compensation decreases ventilation, causing PaCO₂ to become .

04
Choose one
1 point

A patient with persistent vomiting develops metabolic alkalosis. Which associated manifestations may occur?

  1. A

    Weakness or cramps, sometimes related to low potassium or volume depletion

  2. B

    Tingling that proves the cause is anxiety

  3. C

    Drowsiness caused by renal bicarbonate retention

  4. D

    Deep, rapid breathing as the typical compensation

05
Choose all
1 point

Which conditions can cause respiratory acidosis through inadequate ventilation? Select all that apply.

  1. A

    Sedative or opioid effects

  2. B

    Pain causing excessive ventilation

  3. C

    Neuromuscular weakness

  4. D

    Airway or lung disease that impairs ventilation

06
Fill in the blank
1 point

In respiratory alkalosis, the kidneys compensate by . Greater renal compensation develops over .

07
Written response
1 point

For metabolic acidosis with HCO₃⁻ 16 mEq/L, use Winter’s formula, PaCO2=(1.5×HCO3−)+8\mathrm{PaCO_2} = (1.5 \times \mathrm{HCO_3^-}) + 8, to calculate the predicted PaCO₂ midpoint. Enter the value in mm Hg, before applying the ±2\pm 2 range.

08
Choose all
1 point

A patient has an abnormal ABG. Which actions align with the recommended treatment priorities? Select all that apply.

  1. A

    Assess airway, breathing, circulation, mental status, and severity

  2. B

    Address the underlying illness or fluid and electrolyte problem

  3. C

    Immediately normalize the pH regardless of the cause

  4. D

    Reassess the patient and consider a mixed disorder if compensation is unexpected

09
True or false
1 point

True or false: Compensation for a primary acid–base disorder normally overshoots and moves the pH to the opposite side of the normal range.

  1. A

    True

  2. B

    False

10
Choose one
1 point

A patient with metabolic acidosis has HCO₃⁻ 10 mEq/L and a measured PaCO₂ of 35 mm Hg. Using Winter’s formula, PaCO2=(1.5×HCO3−)+8±2\mathrm{PaCO_2} = (1.5 \times \mathrm{HCO_3^-}) + 8 \pm 2 mm Hg, which interpretation is most appropriate?

  1. A

    The PaCO₂ is within the expected compensatory range

  2. B

    An additional respiratory alkalosis is suggested

  3. C

    An additional respiratory acidosis or inadequate ventilatory compensation is suggested

  4. D

    The bicarbonate value rules out a mixed disorder

11
Open ended
1 point

A patient with fever and rapid breathing has pH 7.50, PaCO₂ 28 mm Hg, and HCO₃⁻ 21 mEq/L. Identify the primary acid–base disorder and explain whether rapid breathing should automatically be treated as anxiety.

12
Choose one
1 point

What can be concluded from an ABG when its values show a clear acid–base pattern?

  1. A

    The ABG by itself establishes the underlying cause

  2. B

    The ABG identifies an acid–base pattern; the underlying cause requires clinical evaluation

  3. C

    The pH alone identifies the cause

  4. D

    The cause can be determined only from the bicarbonate value

13
Choose one
1 point

A patient with stable chronic lung disease has pH 7.34, PaCO₂ 60 mm Hg, and HCO₃⁻ 32 mEq/L. Which interpretation best explains the elevated bicarbonate?

  1. A

    Chronic respiratory acidosis with renal compensation

  2. B

    Acute respiratory alkalosis with renal compensation

  3. C

    Metabolic alkalosis with respiratory compensation

  4. D

    Metabolic acidosis with respiratory compensation

14
True or false
1 point

In an uncomplicated acid–base disorder, compensation normally moves the pH toward normal without overshooting or fully normalizing it.

  1. A

    True

  2. B

    False

15
Choose one
1 point

An adult has an arterial blood gas with pH 7.317.31, PaCO₂ 3030 mm Hg, and HCO₃⁻ 1515 mEq/L. Which primary acid–base disorder best explains the acidemia?

  1. A

    Metabolic acidosis

  2. B

    Respiratory acidosis

  3. C

    Metabolic alkalosis

  4. D

    Respiratory alkalosis

16
Choose one
1 point

A patient develops metabolic acidosis during ketoacidosis. Which mechanism from the listed causes best accounts for the acidosis?

  1. A

    Loss of acid through vomiting

  2. B

    Loss of bicarbonate through diarrhea

  3. C

    Increased acid production

  4. D

    Reduced ventilation

17
Written response
1 point

In chronic respiratory acidosis, what renal adaptation is suggested by an elevated HCO₃⁻?

18
Written response
1 point

Severe diarrhea can cause metabolic acidosis. What direct acid–base mechanism explains this effect?

19
Choose one
1 point

Which symptom pair can occur with metabolic alkalosis, sometimes in association with low potassium or volume depletion?

  1. A

    Drowsiness and headache

  2. B

    Weakness and cramps

  3. C

    Lightheadedness and tingling

  4. D

    Deep, rapid breathing

20
Written response
1 point

A patient who is difficult to awaken after taking sedating medication has a pH of 7.25, PaCO₂ of 60 mm Hg, and HCO₃⁻ of 26 mEq/L. What is the primary disorder?