True or false: Compensation moves pH toward normal but does not itself correct the underlying cause.
3 Compensation and Mixed Acid–Base Disorders Online Quiz Questions
Use this free practice quiz with 20 questions to review 3 Compensation and Mixed Acid–Base Disorders, test your knowledge, and prepare for your next test or exam.
A patient with metabolic acidosis has an HCO₃⁻ of 12 mEq/L and a measured PaCO₂ of 30 mm Hg. Which statement best describes the measured PaCO₂ compared with the expected range from Winter’s formula?
- A
It is within the expected range of 24–28 mm Hg.
- B
It is above the expected range of 24–28 mm Hg.
- C
It is below the expected range of 24–28 mm Hg.
- D
It is within the expected range only if PaCO₂ is above 40 mm Hg.
In acute respiratory alkalosis, HCO₃⁻ falls about mEq/L for each 10-mm Hg decrease in PaCO₂ below 40 mm Hg.
For chronic respiratory acidosis with PaCO₂ at 70 mm Hg, what is the lower bound of the expected HCO₃⁻ range? Use a baseline PaCO₂ of 40 mm Hg and HCO₃⁻ of 24 mEq/L.
In metabolic alkalosis, HCO₃⁻ is 34 mEq/L. Using the practical estimate 40+0.6×(HCO3−−24), what PaCO₂ is expected?
- A
40 mm Hg
- B
44 mm Hg
- C
46 mm Hg
- D
55 mm Hg
True or false: Renal compensation takes longer than respiratory compensation, so the history can help distinguish acute from chronic respiratory disorders.
- A
True
- B
False
For metabolic acidosis, select all statements that correctly interpret the measured PaCO₂ relative to its expected compensatory range.
- A
A PaCO₂ higher than the expected range suggests an additional respiratory acidosis.
- B
A PaCO₂ lower than the expected range suggests an additional respiratory alkalosis.
- C
A near-normal pH rules out a mixed acid–base disorder.
- D
A PaCO₂ within the expected range supports a simple disorder with compensation.
In chronic respiratory alkalosis, HCO₃⁻ falls about mEq/L for each 10-mm Hg decrease in PaCO₂ below 40 mm Hg.
PaCO₂ is 60 mm Hg, or 20 mm Hg above baseline. Select the expected HCO₃⁻ estimates for both an acute and a chronic respiratory acidosis.
- A
Acute respiratory acidosis predicts HCO₃⁻ near 26 mEq/L.
- B
Acute respiratory acidosis predicts HCO₃⁻ near 30–32 mEq/L.
- C
Chronic respiratory acidosis predicts HCO₃⁻ near 30–32 mEq/L.
- D
Chronic respiratory acidosis predicts HCO₃⁻ near 26 mEq/L.
A patient with explicitly acute respiratory acidosis has PaCO₂ of 60 mm Hg and HCO₃⁻ of 32 mEq/L. What does the bicarbonate result suggest?
- A
The bicarbonate is appropriate for acute compensation.
- B
An additional metabolic alkalosis is suggested.
- C
An additional respiratory alkalosis is suggested.
- D
An additional metabolic acidosis is suggested.
A patient has pH 7.40, HCO₃⁻ 12 mEq/L, and PaCO₂ 20 mm Hg. Use Winter’s formula to determine whether this is a simple metabolic acidosis with compensation or a mixed disorder. Explain how the near-normal pH affects your conclusion.
A patient has chronic respiratory alkalosis with PaCO₂ of 30 mm Hg and HCO₃⁻ of 18 mEq/L. Which statement best characterizes the bicarbonate relative to the expected chronic range?
- A
The HCO₃⁻ is below the expected chronic compensatory range.
- B
The HCO₃⁻ is within the expected chronic compensatory range.
- C
The HCO₃⁻ is above the expected chronic compensatory range.
- D
The HCO₃⁻ is expected only for acute respiratory alkalosis.
True or false: In metabolic alkalosis, compensatory PaCO₂ usually does not rise above about 55 mm Hg.
- A
True
- B
False
Which statement correctly describes the compensatory response to primary acid–base disturbances?
- A
The kidneys respond to metabolic disturbances, while the lungs respond to respiratory disturbances.
- B
The lungs respond to metabolic disturbances, while the kidneys respond to respiratory disturbances.
- C
Both systems respond only to respiratory disturbances.
- D
Neither system changes unless the underlying cause is corrected.
For metabolic acidosis with HCO3−=14 mEq/L, what PaCO₂ range is expected by Winter’s formula, including its ±2 mm Hg allowance?
- A
19–23 mm Hg
- B
25–29 mm Hg
- C
27–31 mm Hg
- D
29–33 mm Hg
For metabolic alkalosis with HCO3−=34 mEq/L, calculate the estimated compensatory PaCO₂ using 40+0.6×(HCO3−−24). Enter the value in mm Hg.
In an acute respiratory acidosis with PaCO₂ of 70 mm Hg, which HCO3− value is closest to the expected compensatory value?
- A
24 mEq/L
- B
27 mEq/L
- C
33 mEq/L
- D
36 mEq/L
In chronic respiratory alkalosis with PaCO₂ of 20 mm Hg, what HCO3− range is expected from the stated rule of thumb?
- A
4–8 mEq/L
- B
6–10 mEq/L
- C
10–14 mEq/L
- D
14–18 mEq/L
For chronic respiratory acidosis with PaCO₂ of 60 mm Hg, use the lower estimate of 3 mEq/L bicarbonate rise per 10-mm Hg PaCO₂ rise above 40. What is the resulting estimated HCO3− in mEq/L?
When interpreting a patient's acid–base results using an approximate compensation estimate, what should be considered alongside the estimate?
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