What is anemia?
Anemia is a reduction in hemoglobin or red blood cells that can limit oxygen delivery to tissues.
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What is anemia?
Anemia is a reduction in hemoglobin or red blood cells that can limit oxygen delivery to tissues.
What initial test is used to evaluate anemia?
A complete blood count (CBC) measures hemoglobin and red blood cells and is the starting point for evaluating anemia.
What iron-study pattern supports iron-deficiency anemia?
Low ferritin, low serum iron, and high total iron-binding capacity (TIBC) support iron-deficiency anemia.
What iron-study pattern suggests anemia of inflammation?
Anemia of inflammation commonly has low serum iron, low TIBC, and normal-to-high ferritin.
What deficiency can link macrocytosis with neurologic symptoms?
Vitamin B12 deficiency can cause macrocytic anemia with neurologic findings such as numbness or difficulty with balance; confirm and treat it promptly.
What feature helps distinguish folate deficiency from vitamin B12 deficiency?
Neurologic symptoms are generally absent in folate deficiency, unlike the neurologic pattern that can occur with vitamin B12 deficiency.
What laboratory pattern indicates hemolysis?
Increased reticulocytes, indirect bilirubin, and lactate dehydrogenase (LDH), with low haptoglobin, indicate red-cell destruction.
What blood-count pattern can occur in aplastic anemia?
Aplastic anemia involves bone-marrow failure and can lower red cells, white cells, and platelets, increasing risks of anemia, infection, and bleeding.
How can chronic kidney disease contribute to anemia?
Chronic kidney disease can reduce erythropoietin signaling and red-cell production, contributing to anemia.
What is the general principle for treating anemia?
Treat the identified cause; use iron when iron deficiency is established rather than giving it automatically for any anemia.
What does MCV help classify?
Mean corpuscular volume (MCV) helps classify anemia by red-cell size and guide further evaluation.
What does the reticulocyte count help assess?
The reticulocyte count helps assess the marrow response and distinguish reduced red-cell production from blood loss or destruction.
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