Use this free practice quiz with 20 questions to review 2 Leukemia, test your knowledge, and prepare for your next test or exam.
A leukemia described as acute generally involves more immature cells and may progress more rapidly than a chronic leukemia, which generally involves more mature cells and may develop more slowly. Is this statement true or false?
True
False
A patient has a rapidly progressing leukemia, and testing identifies immature cells of lymphoid lineage. Which leukemia subtype best fits?
AML
CML
ALL
CLL
Which gene fusion supports a diagnosis of CML and can also be relevant in some cases of ALL? Enter the gene fusion symbol.
When leukemia cells are analyzed to characterize their cell features and markers, evaluation commonly includes .
A CBC and blood smear suggest acute leukemia. Which evaluation best helps establish the diagnosis and identify the specific subtype?
A CBC alone, because it establishes the specific leukemia subtype
A CBC with differential, bone-marrow aspirate and biopsy, cell studies, and cytogenetic or molecular testing
A blood smear alone, followed by treatment based only on symptoms
A CBC and imaging, without testing the leukemia cells
A very high white blood cell count in a patient with leukemia does not necessarily mean the patient has enough functional infection-fighting cells. Is this statement true or false?
True
False
Leukemic cells can crowd out normal bone-marrow production. Select all correct connections between reduced normal blood-cell production and clinical findings.
Reduced red blood cell production can contribute to fatigue and pallor.
Reduced functional neutrophils can increase infection risk.
Low platelets can contribute to bruising and bleeding.
A high white blood cell count always means infection-fighting function is adequate.
A patient has newly diagnosed, chronic-phase CML with BCR::ABL1. Which treatment approach is standard for this disease setting?
A BCR::ABL1-targeting tyrosine kinase inhibitor
Active surveillance alone in every newly diagnosed case
ATRA with arsenic trioxide as the standard approach for all CML
Empiric antimicrobial treatment as the primary leukemia therapy
For a patient with asymptomatic CLL and no signs of progression, active surveillance is commonly used, with treatment considered if the disease becomes symptomatic or progressive. Is this statement true or false?
True
False
Because prompt treatment is critical when APL is suspected, the treating team initiates as soon as the disease is suspected.
A patient with suspected APL has gum bleeding, widespread bruising, low fibrinogen, and prolonged clotting times. What serious coagulation complication is a priority concern? Enter its abbreviation.
After starting treatment for acute leukemia, a patient develops nausea, muscle cramps, and reduced urine output. Which laboratory changes are consistent with tumor lysis syndrome? Select all that apply.
Increased uric acid
Decreased potassium
Increased phosphate
Decreased calcium
Decreased uric acid
A patient receiving leukemia treatment has neutropenia and a temperature of 38°C (100.4°F). What is the priority response?
Wait to see whether additional infection symptoms develop.
Give routine comfort measures and report the fever at the next appointment.
Notify the oncology team immediately and follow the febrile-neutropenia protocol.
Recheck the temperature later before taking any action.
A patient being treated for acute leukemia develops findings concerning for tumor lysis syndrome. Describe the immediate team notification and the key monitoring and ordered management measures.
Which leukemia subtype is both chronic and lymphoid?
AML
ALL
CML
CLL
A patient with leukemia has repeated infections, fatigue, pallor, and easy bruising. Which change best explains the increased infection risk?
Excess red blood cell production
Reduced numbers of functional neutrophils
Increased platelet production
Excess production of mature lymphocytes
For a patient with asymptomatic CLL and no signs of progression, which approach is commonly used?
Begin treatment immediately, regardless of symptoms or progression
Use active surveillance while the disease remains asymptomatic and without signs of progression
Use a BCR::ABL1-targeting tyrosine kinase inhibitor
Treat with ATRA and arsenic trioxide
A CBC and blood smear suggest acute leukemia. Which evaluation best helps establish the diagnosis and characterize the leukemia cells?
Repeat the blood smear only, then assign a subtype from symptoms
Bone-marrow aspirate and biopsy, with leukemia-cell morphology and flow cytometry
Imaging alone to locate the affected blood-forming tissue
A platelet count alone to distinguish acute leukemia subtypes
What is the standard abbreviation for chronic lymphocytic leukemia?
What is the standard abbreviation for disseminated intravascular coagulation, a possible complication of APL-associated coagulopathy?
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