What is the purpose of levothyroxine?
Levothyroxine is thyroid-hormone replacement therapy.
Study 3 Thyroid Medications with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
What is the purpose of levothyroxine?
Levothyroxine is thyroid-hormone replacement therapy.
How should levothyroxine be taken in relation to food?
Take it consistently on an empty stomach.
How far apart should levothyroxine and iron or calcium be taken?
Separate levothyroxine from iron or calcium by at least 4 hours because these agents can reduce its absorption.
When is TSH generally reassessed after a levothyroxine dose change?
Reassess TSH in about 6–8 weeks.
What can new palpitations and tremor suggest in a patient taking levothyroxine?
Palpitations, tremor, heat intolerance, and insomnia may indicate excessive thyroid-hormone replacement.
How should a patient respond to possible excess levothyroxine effects?
Have the symptoms and thyroid status reviewed; do not change the dose independently.
What do methimazole and propylthiouracil do?
Methimazole and propylthiouracil reduce new thyroid-hormone production.
What serious complication can fever or sore throat signal during antithyroid therapy?
Fever or a severe sore throat can signal agranulocytosis, a rare but potentially life-threatening reduction in white blood cells.
What should a patient taking methimazole do if fever and severe sore throat develop?
Contact the prescriber promptly; evaluation should include a white blood cell count with differential. Do not take more doses until instructed.
What monitoring concern arises when methimazole is taken with warfarin?
Methimazole can increase warfarin's effect, so PT/INR monitoring may need attention, especially when treatment or thyroid status changes.
What major safety warning applies to propylthiouracil?
Propylthiouracil carries a boxed warning for severe, sometimes fatal liver injury.
Which symptoms during propylthiouracil treatment may signal liver injury?
Jaundice, dark urine, or right-upper-abdominal pain may indicate liver injury.
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