5 Cardiac Glycosides Free Online FlashCards

How can digoxin help control chronic atrial fibrillation?

It slows conduction through the AV node, helping control the ventricular rate.

What benefits may digoxin provide in adults with heart failure?

In some adults with heart failure, it may improve symptoms and reduce heart-failure-related hospitalizations, but it has not been shown to reduce mortality.

Which gastrointestinal and visual symptoms may suggest digoxin toxicity?

Nausea, poor appetite, and yellow-tinted vision can be signs of possible digoxin toxicity.

Does a digoxin level at or below 2 ng/mL rule out toxicity?

No. Toxicity can occur even when a measured digoxin level is not above 2 ng/mL; symptoms and clinical findings matter.

How can low potassium or magnesium affect digoxin toxicity risk?

Low potassium or low magnesium can make the heart more susceptible to digoxin toxicity.

When should a digoxin blood sample generally be collected?

Collect it at least 6 hours after the last dose, or just before the next dose.

Why does reduced kidney function raise concern for digoxin accumulation?

Digoxin is primarily excreted by the kidneys. Reduced kidney function can slow its clearance, causing accumulation and increasing toxicity risk.

How can amiodarone affect digoxin concentrations?

Amiodarone can raise digoxin concentrations, so the prescriber may need to adjust the dose and monitor levels.

Does digoxin convert atrial fibrillation to a normal rhythm?

No. Digoxin can control the ventricular rate, but it does not convert atrial fibrillation to a normal rhythm.

Which heart-rate or conduction changes may signal digoxin toxicity?

A slow pulse, rhythm disturbances, or impaired cardiac conduction can indicate possible digoxin toxicity.

Why can potassium-wasting diuretics increase digoxin toxicity risk?

They can lower potassium, which may increase susceptibility to digoxin toxicity.

Why can a digoxin level taken soon after a dose be misleading?

Digoxin needs time to distribute into tissues, so an early sample can give a misleading result.