01
Front
What is the primary mechanism of SSRIs?
Back
SSRIs primarily inhibit serotonin reuptake.
Free Online Flashcard Deck
2 Antidepressants Free Online FlashCards
Study 2 Antidepressants with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
12 cards
02
Front
Which common mirtazapine effects may matter when selecting treatment?
Back
Mirtazapine commonly causes somnolence and increased appetite or weight; these effects may be relevant to selection but can also be undesirable.
03
Front
Why is bupropion contraindicated with a history of bulimia?
Back
Bupropion is contraindicated with a current or prior diagnosis of bulimia or anorexia nervosa because of increased seizure risk.
04
Front
What risk should be considered with sertraline, regular NSAID use, and warfarin?
Back
Increased bleeding risk deserves attention. The care team should review medications and assess appropriate monitoring, including anticoagulation monitoring when indicated.
05
Front
What history should be assessed before starting an antidepressant for depression?
Back
Assess personal or family history of bipolar disorder, mania, or hypomania because antidepressants can precipitate mania or hypomania in some people with bipolar disorder.
06
Front
When is close monitoring for worsening mood or suicidal thoughts especially important?
Back
Monitor especially closely early in treatment and after a dose change. New or worsening suicidal thoughts require prompt clinical attention.
07
Front
Should a patient abruptly stop an antidepressant after feeling better?
Back
No. Discuss stopping with the prescriber; many antidepressants should be tapered to reduce discontinuation symptoms.
08
Front
What is the primary mechanism of SNRIs?
Back
SNRIs inhibit serotonin and norepinephrine reuptake.
09
Front
Which neurotransmitters' reuptake does bupropion primarily inhibit?
Back
Bupropion primarily inhibits norepinephrine and dopamine reuptake.
10
Front
How do MAOIs affect monoamine oxidase?
Back
MAOIs inhibit monoamine oxidase, an enzyme that breaks down monoamines.
11
Front
What adverse effects are important with TCAs?
Back
TCAs can cause anticholinergic effects, orthostatic hypotension, and cardiac toxicity in overdose.
12
Front
What cardiovascular measure may need monitoring with venlafaxine?
Back
Venlafaxine can increase blood pressure, so blood-pressure monitoring may be appropriate.
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