Which antidepressant class inhibits the reuptake of both serotonin and norepinephrine?
2 Antidepressants Online Quiz Questions
Use this free practice quiz with 20 questions to review 2 Antidepressants, test your knowledge, and prepare for your next test or exam.
Close monitoring for worsening mood or suicidal thoughts is especially important early in antidepressant treatment and after a dose change.
- A
True
- B
False
During phenelzine treatment, tyramine can trigger a .
A patient with depression reports low appetite and difficulty sleeping. Which antidepressant's common adverse-effect profile may be relevant to discuss because it can increase appetite and cause somnolence?
A patient’s medication review raises concern about anticholinergic effects, orthostatic hypotension, and cardiac toxicity in overdose. Which antidepressant class best matches this adverse-effect profile?
- A
An SSRI
- B
A tricyclic antidepressant (TCA)
- C
Bupropion
- D
An SNRI
Combining an SSRI with an MAOI can cause the potentially serious reaction known as .
A single fixed washout interval is appropriate for every switch between an SSRI and an MAOI.
- A
True
- B
False
When a patient feels better and wants to stop an antidepressant, what general approach should they discuss with the prescriber instead of stopping abruptly?
A patient starting an antidepressant has a clinical reason to pay attention to blood pressure. Which medication may raise blood pressure, making monitoring potentially appropriate?
- A
Mirtazapine
- B
A tricyclic antidepressant
- C
Venlafaxine
- D
Bupropion
A patient taking sertraline regularly uses an NSAID and also takes warfarin. Which considerations or actions are appropriate for the care team? Select all that apply.
- A
Consider increased bleeding risk.
- B
Stop warfarin immediately without consulting the care team.
- C
Review the patient's full medication list.
- D
Assess appropriate monitoring, including anticoagulation monitoring when indicated.
Before starting an antidepressant for depressive symptoms, which histories should be assessed to help guide treatment? Select all that apply.
- A
Ask about personal or family history of bipolar disorder.
- B
Screen only for a personal history of unipolar depression.
- C
Ask about personal or family history of mania.
- D
Ask about personal or family history of hypomania.
A patient with a history of bulimia asks about taking bupropion for depression. Which response best reflects the safety concern?
- A
Bupropion is preferred because bulimia prevents seizures.
- B
Bupropion is contraindicated because of increased seizure risk; the history should be discussed with the prescriber.
- C
The history is relevant only if the patient currently has symptoms.
- D
The patient should start bupropion and report any problems later.
A patient with depressive symptoms asks why a particular antidepressant cannot be selected based only on the symptoms they report. Explain why treatment selection should be individualized and name at least two other factors that the care team should consider.
True or false: Feeling better is, by itself, a reason to abruptly stop an antidepressant without consulting the prescriber.
- A
True
- B
False
Which mechanism best describes bupropion?
- A
Primarily inhibit norepinephrine and dopamine reuptake
- B
Inhibit serotonin reuptake
- C
Inhibit serotonin and norepinephrine reuptake
- D
Inhibit monoamine oxidase
A patient’s medication is associated with anticholinergic effects, orthostatic hypotension, and cardiac toxicity in overdose. Which antidepressant category best fits this profile?
- A
A tricyclic antidepressant (TCA)
- B
Mirtazapine
- C
Venlafaxine
- D
Bupropion
A patient taking venlafaxine is being assessed for a possible medication-related change that may warrant monitoring. What adverse effect should the care team watch for? Enter the effect as a concise medical term.
A patient with depression reports low appetite and difficulty sleeping. Which medication’s adverse-effect profile might be relevant to selection, while also requiring discussion of a possible trade-off?
- A
Venlafaxine, because it commonly increases appetite and causes somnolence
- B
A TCA, because its main trade-off is increased appetite and somnolence
- C
Mirtazapine, while discussing possible unwanted somnolence and weight gain
- D
Bupropion, because its typical effect is increased appetite and somnolence
A patient with a history of bulimia asks about bupropion for depression. Which safety issue should guide the discussion?
- A
A history of bulimia makes increased appetite the only relevant concern
- B
Bupropion is contraindicated because the history is associated with increased seizure risk
- C
Bupropion should be used without further discussion because bulimia does not affect its safety
- D
The history means blood-pressure monitoring is the only necessary precaution
A patient taking phenelzine needs counseling about tyramine-containing foods. What acute complication can tyramine trigger? Enter the complication as a concise medical term.
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