Iron salts taken with carbidopa/levodopa can reduce its and effectiveness.
8 Integrated CNS Medication Cases Online Quiz Questions
Use this free practice quiz with 20 questions to review 8 Integrated CNS Medication Cases, test your knowledge, and prepare for your next test or exam.
True or false: Adding haloperidol can worsen rigidity and slowness in a person with Parkinson’s disease and reduce levodopa’s therapeutic effect.
- A
True
- B
False
A patient reports sleep-driving after taking zolpidem. Which response is most appropriate?
- A
Continue zolpidem as usual unless sleep-driving happens again.
- B
Discontinue zolpidem and contact the prescriber promptly; do not take another dose unless a clinician reassesses the situation.
- C
Take an extra dose at bedtime to prevent waking during the night.
- D
Stop alprazolam abruptly instead, but continue zolpidem.
Valproate can increase lamotrigine , while rapid lamotrigine dose escalation increases the risk of a serious .
A patient taking an opioid asks which other substances could add to the risk of profound sedation and respiratory depression. Select all that apply.
- A
Alprazolam
- B
Zolpidem
- C
A non-sedating antacid
- D
Alcohol
True or false: A person who regularly uses a benzodiazepine should stop it abruptly to avoid becoming dependent.
- A
True
- B
False
A person who could become pregnant is considering valproate for bipolar disorder. Which counseling approach is most appropriate?
- A
Discuss pregnancy intentions and alternatives, and carefully assess risks and benefits because exposure can cause congenital malformations and neurodevelopmental harm.
- B
Reassure the patient that valproate has no important risks during pregnancy.
- C
Discuss pregnancy intentions only after a pregnancy is confirmed.
- D
Avoid discussing alternatives because the risks are limited to the first few days of treatment.
When considering valproate for someone who could become pregnant, select all appropriate counseling or monitoring points supported by the material.
- A
Discuss pregnancy intentions and alternatives.
- B
Obtain liver tests before treatment and monitor as directed.
- C
Consider the risk of congenital malformations and neurodevelopmental harm from pregnancy exposure.
- D
Monitor absolute neutrophil count as the primary valproate-specific test.
A patient stable on lithium starts hydrochlorothiazide, uses ibuprofen regularly, and then develops vomiting, diarrhea, worsening tremor, unsteady walking, and confusion. What is the leading medication-related concern?
- A
The symptoms are most consistent with an expected effect of hydrochlorothiazide, so no medication review is needed.
- B
Lithium toxicity is a major concern; hydrochlorothiazide, ibuprofen, and fluid loss from vomiting and diarrhea may all contribute.
- C
Ibuprofen lowers lithium concentrations, while diarrhea protects against lithium toxicity.
- D
The main concern is serotonin syndrome caused by the combination of lithium and hydrochlorothiazide.
A patient taking lithium develops worsening tremor, unsteady walking, and confusion after several days of vomiting and diarrhea. Describe what should be assessed urgently and what routine monitoring supports safer lithium treatment.
True or false: Agitation, sweating, diarrhea, tremor, and unusually brisk reflexes in a patient taking tramadol who is about to start sertraline are concerning for serotonin syndrome and warrant urgent clinical assessment.
- A
True
- B
False
A patient reports sleep-driving after taking zolpidem. Which response best reflects the recommended safety action?
- A
Continue zolpidem but take it earlier in the evening.
- B
Discontinue zolpidem and contact the prescriber promptly.
- C
Take a smaller dose the next night and report the episode at the next routine visit.
- D
Add an over-the-counter sleep aid to prevent another episode.
A patient taking clozapine develops fever and a sore throat. Which blood count test is important to assess for clozapine-related severe neutropenia?
A patient stopped an MAOI and is considering starting sertraline. What is the minimum number of days after stopping the MAOI before sertraline should be started?
A patient takes an iron-containing multivitamin at the same time as carbidopa/levodopa. What interaction should the care team consider?
- A
Iron increases levodopa absorption, so the Parkinson’s medication dose should be reduced.
- B
Iron has no effect on carbidopa/levodopa, so timing does not need review.
- C
Iron can reduce carbidopa/levodopa absorption, so the care team should review the timing and product-specific instructions.
- D
Iron blocks dopamine receptors, so the multivitamin should always be permanently stopped.
A patient regularly takes alprazolam and is prescribed an opioid for acute pain. What is the main safety risk of combining these medicines?
- A
The combination mainly increases the risk of high blood pressure without affecting breathing.
- B
The combination can cause profound sedation and respiratory depression, potentially leading to coma or death.
- C
The combination reliably prevents opioid-related breathing problems.
- D
The combination reduces the sedative effects of both medicines.
A patient stable on lithium starts hydrochlorothiazide, uses ibuprofen regularly, and then develops vomiting and diarrhea followed by worsening tremor and confusion. Which explanation best accounts for the increased risk of lithium toxicity?
- A
Hydrochlorothiazide and ibuprofen lower lithium concentrations, while vomiting and diarrhea protect against toxicity.
- B
Only the patient’s tremor could contribute; the medication changes and fluid loss are unrelated.
- C
Hydrochlorothiazide and ibuprofen can raise lithium concentrations, and fluid loss from vomiting and diarrhea can further increase toxicity risk.
- D
Ibuprofen prevents lithium accumulation, but hydrochlorothiazide may cause a harmless temporary tremor.
A patient taking tramadol develops agitation, sweating, diarrhea, tremor, and unusually brisk reflexes. What serious drug reaction should be considered?
When considering valproate for someone who could become pregnant, which risk should be discussed during individualized treatment planning?
- A
Valproate is known only to cause temporary nausea during pregnancy, so pregnancy planning is not relevant.
- B
Valproate exposure during pregnancy can cause major congenital malformations, including neural tube defects, and neurodevelopmental harm.
- C
Valproate prevents neural tube defects, so it is preferred when someone could become pregnant.
- D
Valproate poses no pregnancy-related risk if liver tests are normal.
Before starting an antidepressant, which two mood-state histories should be screened for because they can affect treatment choice? Enter both categories.
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