01
Front
Which medication is commonly used for absence seizures alone?
Back
Ethosuximide is a commonly used targeted option when absence seizures occur alone.
Free Online Flashcard Deck
5 Anticonvulsants Free Online FlashCards
Study 5 Anticonvulsants with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
12 cards
02
Front
What is a principal mechanism of ethosuximide?
Back
Ethosuximide blocks T-type calcium currents, a mechanism especially relevant to absence seizures.
03
Front
What behavioral changes can occur with levetiracetam?
Back
Levetiracetam can cause behavioral changes such as irritability, aggression, and mood symptoms.
04
Front
How does valproate affect lamotrigine concentrations and initiation?
Back
Valproate raises lamotrigine concentrations by slightly more than twofold, so initiation and dose increases follow a slower recommended schedule.
05
Front
What major fetal risks are associated with valproate exposure during pregnancy?
Back
Valproate exposure is associated with major congenital malformations, including neural tube defects, and adverse neurodevelopmental outcomes.
06
Front
Name patient-specific factors that can affect antiseizure medication choice.
Back
Relevant factors include other medical or psychiatric conditions, adverse-effect and interaction risks, kidney or liver function, age, and pregnancy potential.
07
Front
What may change if absence seizures occur alongside other generalized seizure types?
Back
A broader-spectrum medication may be considered, with the choice guided by the full syndrome and patient-specific factors.
08
Front
Which medication can worsen absence or myoclonic seizures?
Back
Carbamazepine can worsen absence or myoclonic seizures.
09
Front
Which synaptic vesicle protein does levetiracetam modulate?
Back
Levetiracetam modulates synaptic vesicle protein SV2A.
10
Front
What is a principal mechanism of phenytoin?
Back
Phenytoin inhibits voltage-gated sodium channels.
11
Front
What serious safety risk should be watched for when starting lamotrigine?
Back
Lamotrigine can cause serious skin reactions, including Stevens–Johnson syndrome; a new rash should be reported promptly for medical advice.
12
Front
Why can an interacting medicine that inhibits phenytoin metabolism be hazardous?
Back
Its saturable metabolism and interactions can raise phenytoin concentrations and increase toxicity risk.
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