What defines an autoimmune disease?
Autoimmune diseases occur when the immune system mistakenly targets the body’s own cells or tissues.
Study 2 Autoimmune Diseases with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
What defines an autoimmune disease?
Autoimmune diseases occur when the immune system mistakenly targets the body’s own cells or tissues.
What is self-tolerance?
Self-tolerance limits immune responses against the body’s own tissues while preserving the ability to respond to infections and other threats.
What can self-reactive B cells produce?
Self-reactive B cells may produce autoantibodies that target the body’s own tissues.
What factors contribute to autoimmune disease risk?
Risk reflects interactions among genetic susceptibility, immune regulation, and environmental influences. A particular trigger is often unknown.
How does type 1 diabetes illustrate organ-specific autoimmunity?
In type 1 diabetes, immune-mediated destruction of pancreatic beta cells reduces insulin production.
How can autoimmune thyroid diseases affect thyroid function?
Hashimoto thyroiditis may make the thyroid underactive, while Graves disease may make it overactive.
What are common signs of inflammation?
Inflammation may cause pain, warmth, redness, and swelling.
What does autoimmune disease diagnosis generally combine?
Evaluation combines clinical history, physical examination, and targeted tests, while considering affected organs, symptom changes, and alternative causes.
What does a positive autoantibody test establish by itself?
A positive autoantibody result alone does not establish an autoimmune diagnosis; it must be interpreted alongside clinical findings.
Can one blood test rule in or rule out every autoimmune disease?
No single blood test diagnoses all autoimmune diseases, and a negative result does not necessarily rule out every autoimmune condition.
What are the main goals of autoimmune disease treatment?
Treatment aims to reduce harmful inflammation, prevent or limit organ damage, relieve symptoms, and preserve function.
Why must immunosuppressive treatment be monitored?
Immunosuppressive treatment can weaken defenses against infection, so clinicians weigh its benefits against risks and monitor for adverse effects.
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