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Free Practice Quiz Question List

1 Immune System Disorders and Immune Dysfunction Online Quiz Questions

Use this free practice quiz with 20 questions to review 1 Immune System Disorders and Immune Dysfunction, test your knowledge, and prepare for your next test or exam.

20 questions
01
Fill in the blank
1 point

As part of innate immunity, natural killer cells can destroy some .

02
Choose one
1 point

A person develops a delayed rash at the site where poison ivy contacted the skin. Which hypersensitivity type is most characteristic of this reaction?

  1. A

    Type I

  2. B

    Type IV

  3. C

    Type II

  4. D

    Type III

03
Written response
1 point

Which adaptive immune-cell type can become plasma cells that secrete antibodies?

04
True or false
1 point

Innate immune recognition responds by identifying one uniquely specific antigen, rather than by detecting common patterns associated with microbes or tissue damage.

  1. A

    True

  2. B

    False

05
Fill in the blank
1 point

Primary immunodeficiencies arise from .

06
Choose one
1 point

A patient's immune function is impaired because of HIV infection. Which broad category best describes this immunodeficiency?

  1. A

    A primary immunodeficiency

  2. B

    An antibody-mediated hypersensitivity

  3. C

    A secondary immunodeficiency

  4. D

    A Type IV hypersensitivity

07
Choose all
1 point

Which of the following can cause secondary immunodeficiency? Select all that apply.

  1. A

    HIV infection

  2. B

    A genetic defect

  3. C

    Undernutrition

  4. D

    Chemotherapy or radiation

08
Written response
1 point

In Type I hypersensitivity, which antibody class is involved in activating mast cells?

09
True or false
1 point

A person who has recurrent infections necessarily has an immunodeficiency.

  1. A

    True

  2. B

    False

10
Choose one
1 point

Which mechanism characterizes Type II hypersensitivity?

  1. A

    Antigen–antibody complexes deposit in tissues and provoke inflammation.

  2. B

    Antibodies bind antigens on cells or tissues and may trigger destructive mechanisms.

  3. C

    IgE and activated mast cells release inflammatory mediators.

  4. D

    Sensitized T cells cause delayed tissue injury.

11
Choose all
1 point

Which findings can increase concern about a possible immunodeficiency? Select all that apply.

  1. A

    Infections that are unusually severe

  2. B

    Infections that persist or are difficult to treat

  3. C

    Recurrent infections alone, regardless of their nature

  4. D

    Infections caused by uncommon organisms

  5. E

    A suggestive family history

12
Choose one
1 point

A complement protein helps defend the body against a microbe. Which action is consistent with the role of complement?

  1. A

    They become plasma cells that secrete antibodies.

  2. B

    They recognize one uniquely identified antigen and form memory cells.

  3. C

    They can mark microbes for removal or contribute to their destruction.

  4. D

    They cause all delayed hypersensitivity reactions.

13
Open ended
1 point

A person encounters a new virus and later encounters the same virus again. Explain how innate and adaptive immunity contribute during the first encounter and how immune memory can affect the later response.

14
Choose one
1 point

After an initial viral infection, a person encounters the same virus again. Which feature can help produce a faster, targeted response on this later exposure?

  1. A

    Innate immunity responds more rapidly after every exposure because it stores antigen-specific memory.

  2. B

    Adaptive immunity can use memory cells to mount a faster, targeted response.

  3. C

    Complement proteins form memory cells that recognize the virus.

  4. D

    Mucosal barriers become antigen-specific after the first infection.

15
Choose one
1 point

A reaction is caused by antigen–antibody complexes that deposit in tissues and provoke inflammation. Which hypersensitivity type best describes this mechanism?

  1. A

    Type I, because antibodies bind antigens on cells and activate destructive mechanisms.

  2. B

    Type II, because immune complexes deposit in tissues.

  3. C

    Type III, because immune complexes deposit in tissues and provoke inflammation.

  4. D

    Type IV, because IgE activates mast cells.

16
True or false
1 point

True or false: In the Gell–Coombs classification, Type I hypersensitivity is necessarily more severe than reactions of the other types.

  1. A

    True

  2. B

    False

17
Written response
1 point

A patient develops impaired immune function after receiving chemotherapy. What category of immunodeficiency does this represent?

18
Choose one
1 point

An adult is found to have an immune-system defect caused by a genetic change. How should this deficiency be classified?

  1. A

    Primary immunodeficiency, because it arises from a genetic defect.

  2. B

    Secondary immunodeficiency, because a primary form must be recognized in infancy.

  3. C

    Secondary immunodeficiency, because any adult-onset immune problem is acquired.

  4. D

    Hypersensitivity, because genetic defects always cause excessive immune responses.

19
Written response
1 point

Which antigen-presenting cell type helps initiate many T-cell responses?

20
Choose one
1 point

A patient has had several infections. Which conclusion is most consistent with a careful evaluation for possible immunodeficiency?

  1. A

    Recurrent infections by themselves prove an immunodeficiency.

  2. B

    A single common infection establishes which immune component is defective.

  3. C

    A suggestive family history makes clinical assessment unnecessary.

  4. D

    Unusually severe or persistent infections can raise concern, but assessment requires clinical context.