What factors shape infection risk during immunocompromise?
Risk depends on which immune defenses are impaired, how intense and prolonged the treatment is, and factors such as barriers, devices, and exposures.
Study 5 Infections in Immunocompromised Patients with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
What factors shape infection risk during immunocompromise?
Risk depends on which immune defenses are impaired, how intense and prolonged the treatment is, and factors such as barriers, devices, and exposures.
How can people reduce exposure to infections?
Practice hand hygiene, avoid close contact with ill people, and use additional respiratory precautions when appropriate.
What factors shape infection risk after transplantation?
Risk varies with transplant type, immunosuppressive regimen, complications such as graft-versus-host disease, and time since transplant.
Why might infection signs be subtle in an immunocompromised patient?
Fever may be absent or muted, and inflammation may be less obvious, even while infection progresses quickly.
Which infection groups become more likely with neutrophil defects?
Neutrophil defects increase susceptibility to bacterial and fungal infections.
Which infection groups are associated with impaired T-cell function?
Impaired T-cell function increases susceptibility to certain viral, fungal, and protozoal infections.
What is an opportunistic infection?
An opportunistic infection occurs more often or causes more severe disease when immune defenses are weakened.
Which opportunistic infection can occur with advanced HIV?
Pneumocystis jirovecii pneumonia can occur in some people with advanced HIV.
Which foods should be avoided to reduce infection risk?
Avoid higher-risk foods such as unpasteurized products and undercooked meat or eggs.
How is antimicrobial prophylaxis determined?
Preventive medicines may be recommended for specific conditions, treatments, or transplant phases; the care team determines the need and duration.
What should be considered when planning non-live vaccines?
Non-live vaccines are generally safe, though some treatments may reduce the immune response. Review vaccination before immunosuppression when feasible.
Why are live vaccines generally avoided in significant immunocompromise?
Live vaccines are generally avoided in significant immunocompromise because the vaccine organism can cause disease. Exceptions and timing depend on the condition and treatment.
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