01
Front
How does aspirin reduce platelet aggregation?
Back
Aspirin irreversibly inhibits platelet COX-1, reducing thromboxane A₂ formation and platelet aggregation.
Free Online Flashcard Deck
5 Antiplatelet Drugs Free Online FlashCards
Study 5 Antiplatelet Drugs with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
12 cards
02
Front
How do P2Y₁₂ inhibitors reduce platelet activation?
Back
They block platelet P2Y₁₂ receptors, reducing ADP-mediated platelet activation.
03
Front
Are antiplatelet drugs anticoagulants?
Back
They reduce platelet activation and aggregation; they are not anticoagulants.
04
Front
Why combine aspirin with a P2Y₁₂ inhibitor after coronary stenting?
Back
Dual antiplatelet therapy combines aspirin with a P2Y₁₂ inhibitor to reduce recurrent ischemic events and stent-related thrombosis.
05
Front
What is the default DAPT duration after acute coronary syndrome when bleeding risk is not high?
Back
For acute coronary syndrome, DAPT is the default for at least 12 months when bleeding risk is not high; treatment should be individualized.
06
Front
After which type of stroke is antiplatelet therapy commonly used for recurrence prevention?
Back
It is commonly used to prevent recurrence after noncardioembolic ischemic stroke or TIA.
07
Front
Is long-term DAPT routine for all ischemic stroke survivors?
Back
No. It is reserved for selected patients and generally used for a limited period, not routinely long term for all stroke survivors.
08
Front
What gastrointestinal adverse effects can aspirin cause?
Back
Aspirin can cause dyspepsia, peptic ulcers, and gastrointestinal or other bleeding.
09
Front
Why is aspirin generally avoided in children or teenagers with viral infections?
Back
Aspirin should not be given to children or teenagers with viral infections unless specifically directed by a clinician, because of Reye syndrome risk.
10
Front
Which history is a key contraindication to prasugrel?
Back
Prasugrel is contraindicated in patients with a prior stroke or TIA.
11
Front
Which respiratory symptom is associated with ticagrelor?
Back
Ticagrelor can cause dyspnea.
12
Front
Why can omeprazole reduce clopidogrel’s antiplatelet effect?
Back
Clopidogrel partly depends on CYP2C19 for activation; omeprazole and esomeprazole can reduce formation of its active metabolite and lessen its antiplatelet effect.
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