True or false: A leukotriene modifier should be used instead of a rescue inhaler to relieve sudden asthma symptoms.
4 Leukotriene Modifiers and Mucolytics Online Quiz Questions
Use this free practice quiz with 20 questions to review 4 Leukotriene Modifiers and Mucolytics, test your knowledge, and prepare for your next test or exam.
A patient with allergic rhinitis asks whether montelukast is usually the first medicine to try. Which response best reflects its recommended role?
- A
It is generally the first choice for every patient with allergic rhinitis.
- B
It is generally reserved for patients who do not respond to or cannot tolerate alternatives.
- C
It is used for allergic rhinitis only during an acute asthma attack.
- D
It is not used for allergic rhinitis.
Which medication in this group carries a boxed warning for serious neuropsychiatric events?
Montelukast and zafirlukast block receptors.
Which medication inhibits 5-lipoxygenase to reduce leukotriene synthesis?
- A
Montelukast
- B
Zafirlukast
- C
Zileuton
- D
Dornase alfa
Which effects can leukotrienes contribute to in the airways? Select all that apply.
- A
Airway inflammation
- B
Breakdown of extracellular DNA
- C
Bronchoconstriction
- D
Mucus production
- E
Airway swelling
True or false: Both zafirlukast and zileuton can cause liver injury.
- A
True
- B
False
A patient’s medication list is being checked for interactions involving leukotriene modifiers. Which statements are correct? Select all that apply.
- A
Zafirlukast can interact with warfarin.
- B
Montelukast can raise theophylline levels.
- C
Zileuton can raise theophylline levels.
- D
Zileuton can raise warfarin levels.
Inhaled acetylcysteine reduces mucus thickness by disrupting in mucus proteins.
A patient develops progressing bronchospasm during inhaled acetylcysteine treatment. What action is appropriate?
- A
Continue acetylcysteine without reassessment.
- B
Stop acetylcysteine, monitor the patient, and obtain clinical assessment.
- C
Give an additional acetylcysteine dose immediately.
- D
Use acetylcysteine as a rescue treatment for sudden wheezing.
What material does dornase alfa break down in cystic fibrosis sputum?
Explain how inhaled acetylcysteine and dornase alfa differ in the material they act on and how each helps reduce secretion viscosity.
Which medication is used with standard care for cystic fibrosis to improve pulmonary function by reducing DNA-related sputum viscosity?
- A
Zafirlukast
- B
Zileuton
- C
Dornase alfa
- D
Montelukast
True or false: Zileuton can raise theophylline and warfarin levels.
- A
True
- B
False
Which medication carries a boxed warning for serious neuropsychiatric events?
- A
Zafirlukast
- B
Montelukast
- C
Zileuton
- D
Dornase alfa
Which receptor do both montelukast and zafirlukast block?
A patient with cystic fibrosis is prescribed an inhaled enzyme alongside standard care to reduce the viscosity of sputum. Which action explains the enzyme’s effect?
- A
It blocks CysLT₁ receptors to reduce airway inflammation.
- B
It disrupts disulfide bonds in mucus proteins.
- C
It breaks down extracellular DNA in sputum.
- D
It inhibits 5-lipoxygenase to reduce leukotriene synthesis.
Which anticoagulant interacts with zafirlukast?
Which mechanism distinguishes zileuton from montelukast?
- A
It blocks CysLT₁ receptors.
- B
It inhibits 5-lipoxygenase and reduces leukotriene synthesis.
- C
It breaks down extracellular DNA in sputum.
- D
It disrupts disulfide bonds in mucus proteins.
A patient taking montelukast develops new nightmares and marked mood changes. What is the most appropriate advice?
- A
Continue treatment without reporting the symptoms unless breathing worsens.
- B
Contact the prescriber promptly because the symptoms may require stopping the medicine.
- C
Take an extra dose at bedtime to prevent further symptoms.
- D
Use the medicine only when asthma symptoms occur.
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