What effects do leukotrienes have on the airways?
Leukotrienes contribute to airway narrowing, swelling, and inflammation.
Study 5 Leukotriene Modifiers with 12 free online flashcards. Review key terms, definitions, and concepts with this interactive flashcard deck.
What effects do leukotrienes have on the airways?
Leukotrienes contribute to airway narrowing, swelling, and inflammation.
How do montelukast and zafirlukast work?
Montelukast and zafirlukast block cysteinyl-leukotriene receptors.
How does zileuton reduce leukotrienes?
Zileuton inhibits 5-lipoxygenase, reducing leukotriene production.
Are leukotriene modifiers controller medicines or rapid-relief medicines?
They are used for long-term asthma control, not rapid relief of an acute attack.
What should a patient use for sudden asthma symptoms instead of montelukast?
Use the prescribed rescue medicine; montelukast does not rapidly relieve an acute asthma attack.
Do leukotriene modifiers automatically replace prescribed inhaled corticosteroids?
They do not replace a prescribed inhaled corticosteroid unless a clinician specifically changes the treatment plan.
Which leukotriene modifier can prevent exercise-induced bronchoconstriction?
Montelukast can be used to prevent exercise-induced bronchoconstriction.
When is montelukast reserved for allergic rhinitis?
Montelukast may be used for allergic rhinitis when alternative treatments do not work or cannot be tolerated.
What action is advised for new nightmares or marked behavior changes on montelukast?
Stop montelukast and contact the healthcare provider promptly if new nightmares or marked behavior changes occur.
What liver precautions are important with zileuton?
Zileuton can cause liver injury; assess liver enzymes before treatment and monitor them during therapy.
What should be monitored when zileuton is used with warfarin?
Zileuton may increase warfarin effect; monitor prothrombin time and adjust warfarin as needed.
How should zafirlukast be timed around meals?
Take zafirlukast at least 1 hour before or 2 hours after meals because food can reduce its absorption.
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